Results 71 to 80 of about 4,990 (167)
Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy
Journal of Cancer, 2011 Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo.
Yen T. Phung, Dario Barbone, V. Courtney Broaddus, Mitchell Ho
doaj
PharmaceuticalsThe present review provides a detailed and comprehensive discussion on antibody–drug conjugates (ADCs) as an evolving new modality in the current therapeutic landscape of malignant diseases.
Rositsa Mihaylova +3 more
doaj +1 more source
CD30-targeting immunoconjugates and bystander effects [PDF]
Nature Reviews Clinical Oncology, 2015 Shigeo, Masuda +3 more
openaire +2 more sources
Comparative In Vitro Evaluation of Anti-HIV Immunotoxin, Antibody-Drug Conjugate, and Radioimmunoconjugate Targeted by the Same Antibody. [PDF]
Antibodies (Basel)Kuhlmann AS +12 more
europepmc +1 more source
Preclinical characterization of 3p-C-DEPA<sub>-NCS</sub> and 3p-C-DEPA<sub>-TFP</sub>-PEG<sub>4</sub> as potential Actinium-225 bifunctional chelators using DOTA<sub>-NCS</sub> and macropa<sub>-NCS</sub> as benchmarks. [PDF]
EJNMMI Radiopharm ChemPougoue Ketchemen J +8 more
europepmc +1 more source