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Immunodeficiency in DiGeorge Syndrome and Options for Treating Cases with Complete Athymia [PDF]
The commonest association of thymic stromal deficiency resulting in T-cell immunodeficiency is the DiGeorge syndrome (DGS). This results from abnormal development of the third and fourth pharyngeal arches and is most commonly associated with a ...
Davies, EG
exaly +3 more sources
Normalization of Negative Stigma Against HIV/AIDS Patients: A Systematic Review of the Literature [PDF]
Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) is a public health problem that stigmatizes its victims. Mental attacks, as a result of labeling and discrimination, result in psychological suffering and well-being for persons
Machmud, Muslimin+2 more
core +1 more source
Inborn Errors of Immunity (IEI), also known as primary immunodeficiencies, correspond to a heterogeneous group of congenital diseases that primarily affect immune response components. The main clinical manifestations comprise increased susceptibility to infections, autoimmunity, inflammation, allergies and malignancies.
Carolina Sanchez Aranda+2 more
openaire +5 more sources
Primary immunodeficiency [PDF]
Primary immunodeficiency disorder (PID) refers to a heterogeneous group of over 130 disorders that result from defects in immune system development and/or function. PIDs are broadly classified as disorders of adaptive immunity (i.e., T-cell, B-cell or combined immunodeficiencies) or of innate immunity (e.g., phagocyte and complement disorders ...
Christine McCusker, Richard Warrington
openaire +4 more sources
Primary immunodeficiency [PDF]
Primary immunodeficiency disorder (PID) refers to a large heterogeneous group of disorders that result from defects in immune system development and/or function. PIDs are broadly classified as disorders of adaptive immunity (i.e., T cell, B-cell or combined immunodeficiencies) or of innate immunity (e.g., phagocyte and complement disorders).
McCusker, Christine+2 more
openaire +4 more sources
SummaryPrimary immunodeficiencies (PIDs) are uncommon, chronic and severe disorders of the immune system in which patients cannot mount a sufficiently protective immune response, leading to an increased susceptibility to infections. The treatment of choice for PID patients with predominant antibody deficiency is intravenous immunoglobulin (Ig ...
Ballow, Mark+11 more
openaire +6 more sources
Autoimmunity in Immunodeficiency [PDF]
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic defects. Paradoxically, a substantial proportion of PID patients develop autoimmune phenomena in addition to having increased susceptibility to infections from their impaired immunity.
Teresa K. Tarrant+3 more
openaire +3 more sources
The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]
Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Ackley C. D.+50 more
core +1 more source
Viral Reservoirs in Lymph Nodes of FIV-Infected Progressor and Long-Term Non-Progressor Cats during the Asymptomatic Phase. [PDF]
BackgroundExamination of a cohort of cats experimentally infected with feline immunodeficiency virus (FIV) for 5.75 years revealed detectable proviral DNA in peripheral blood mononuclear cells (PBMCs) harvested during the asymptomatic phase, undetectable
Eckstrand, CD+4 more
core +16 more sources
The comparative value of feline virology research: can findings from the feline lentiviral vaccine be translated to humans? [PDF]
Feline immunodeficiency virus (FIV) is a lentivirus of domestic cats that shares several similarities with its human counterpart, human immunodeficiency virus (HIV).
Beczkowski, Paweł M.+5 more
core +1 more source