The role of BST2/tetherin in feline retrovirus infection [PDF]
Pathogenic retroviral infections of mammals have induced the evolution of cellular anti-viral restriction factors and have shaped their biological activities.
Dietrich, Isabelle+2 more
core +1 more source
Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. [PDF]
BackgroundWe reported previously on the emergence and clinical implications of simian immunodeficiency virus (SIVmac251) mutants with a K65R mutation in reverse transcriptase (RT), and the role of CD8+ cell-mediated immune responses in suppressing ...
Bischofberger, Norbert+10 more
core +3 more sources
Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
A Duarte+50 more
core +1 more source
Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody [PDF]
<b>BACKGROUND:</b> In the acute phase of infection with feline immunodeficiency virus (FIV), the virus targets activated CD4+ T cells by utilising CD134 (OX40) as a primary attachment receptor and CXCR4 as a co-receptor.
A Bjorndal+72 more
core +2 more sources
Differential utilization of CD134 as a functional receptor by diverse strains of feline immunodeficiency virus [PDF]
The feline homologue of CD134 (fCD134) is the primary binding receptor for feline immunodeficiency virus (FIV), targeting the virus preferentially to activated CD4+ helper T cells.
Hosie, M.J.+3 more
core +2 more sources
An investigation of the breadth of neutralising antibody response in cats naturally infected with feline immunodeficiency virus [PDF]
Neutralising antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against FIV and HIV infections.
Beczkowski, Pawel+5 more
core +2 more sources
Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H.+7 more
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Neutralization of feline immunodeficiency virus by antibodies targeting the V5 loop of Env [PDF]
Neutralising antibodies (NAbs) play a vital role in vaccine-induced protection against infection with feline immunodeficiency virus (FIV). However, little is known about the appropriate presentation of neutralisation epitopes in order to induce NAbs ...
Hosie, Margaret J.+6 more
core +1 more source
Finding the Fit: A Review of Three Intervention Models for Working with HIV/AIDS Impacted Substance Users who are Homeless [PDF]
This report reflects research on three different models of services for people living with Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS) who are also low-income, substance users and are homeless or at risk of becoming ...
Amy Rynell, Maryann Mason
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Immunodeficiencies caused by infectious diseases. [PDF]
Immunodeficiencies caused by infectious agents may result from disruption of normal host barriers or dysregulation of cellular immunity, the latter serving to promote survival of the infectious agent through immune evasion.
Sykes, Jane
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