Results 21 to 30 of about 632,268 (364)

Sexually transmitted infections and viral hepatitides in patients presenting for non-occupational HIV post-exposure prophylaxis: results of a prospective cohort study

International Journal of Infectious Diseases, 2015
Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited.
Nirojini Sivachandran, Reed A.C. Siemieniuk, Pauline Murphy, Andrea Sharp, Christine Walach, Tania Placido, Isaac I. Bogoch   +6 more
doaj   +1 more source

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.

New England Journal of Medicine, 1997
BACKGROUND The efficacy and safety of adding a protease inhibitor to two nucleoside analogues to treat human immunodeficiency virus type 1 (HIV-1) infection are not clear.
S. Hammer, Kathleen Squires, M. Hughes, Michael Hughes, J. Grimes, L. Demeter, J. Currier, J. Eron, J. Feinberg, H. Balfour, L. Deyton, J. Chodakewitz, M. Fischl, J. Phair, W. Spreen, L. Pedneault, B. Nguyen, Jon C. Cook   +17 more
semanticscholar   +1 more source

Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Frontiers in Public Health, 2022
Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence of few genomic differences between Mtb isolates might indicate TB cases are the result of
Kristin N. Nelson, Sarah Talarico, Shameer Poonja, Clinton J. McDaniel, Martin Cilnis, Alicia H. Chang, Kala Raz, Wendy S. Noboa, Lauren Cowan, Tambi Shaw, James Posey, Benjamin J. Silk   +11 more
doaj   +1 more source

International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

Journal of Clinical Immunology, 2017
Beginning in 1970, a committee was constituted under the auspices of the World Health Organization (WHO) to catalog primary immunodeficiencies. Twenty years later, the International Union of Immunological Societies (IUIS) took the remit of this committee.
Capucine Picard, H. B. Gaspar, W. Al-Herz, A. Bousfiha, J. Casanova, Talal A Chatila, Y. Crow, Y. Crow, C. Cunningham-Rundles, A. Etzioni, J. Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Hans D. Ochs, Eric Oksenhendler, J. Puck, M. Tang, M. Tang, S. Tangye, S. Tangye, T. Torgerson, Kathleen E. Sullivan   +22 more
semanticscholar   +1 more source

Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency

Frontiers in Immunology, 2019
Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency. Patients with CVID are prone to recurrent bacterial infection due to the failure of adequate immunoglobulin production.
Zoya Eskandarian, Zoya Eskandarian, Manfred Fliegauf, Manfred Fliegauf, Alla Bulashevska, Michele Proietti, Rosie Hague, Cristian Roberto Smulski, Desirée Schubert, Klaus Warnatz, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher   +14 more
doaj   +1 more source

Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant

Frontiers in Immunology, 2021
Hemophagocytic lymphohistiocytosis (HLH) is a disorder of uncontrolled immune activation with distinct clinical features including fever, cytopenia, splenomegaly, and sepsis-like symptoms.
Thomas Mika, Deepak Vangala, Matthias Eckhardt, Paul La Rosée, Christoph Lange, Christoph Lange, Kai Lehmberg, Charlotte Wohlschläger, Saskia Biskup, Ilka Fuchs, Jasmin Mann, Stephan Ehl, Klaus Warnatz, Klaus Warnatz, Roland Schroers   +14 more
doaj   +1 more source

Molecular changes associated with increased TNF-α-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans

Immunity & Ageing, 2018
Background Progressive T cell decline in aged humans is associated with a deficiency of naïve (TN) and central memory (TCM) T cells. We have previously reported increased Tumor necrosis factor-α (TNF-α)-induced apoptosis in TN and TCM T cells in aged ...
Sudhir Gupta, Houfen Su, Sudhanshu Agrawal, Sastry Gollapudi   +3 more
doaj   +1 more source

Cytomegaloviruses and Macrophages—Friends and Foes From Early on?

Frontiers in Immunology, 2020
Starting at birth, newborn infants are exposed to numerous microorganisms. Adaptation of the innate immune system to them is a delicate process, with potentially advantageous and harmful implications for health development.
Sebastian Baasch, Sebastian Baasch, Zsolt Ruzsics, Philipp Henneke, Philipp Henneke   +4 more
doaj   +1 more source

Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society–USA Panel

Clinical Infectious Diseases, 2018
Testing for human immunodeficiency virus resistance in drug-naive individuals and in patients in whom antiretroviral treatment (ART) is failing, and the appreciation of the role of testing, are crucial to the prevention and management of failure of ART.
H. Günthard, V. Calvez, R. Paredes, D. Pillay, R. Shafer, A. Wensing, D. M. Jacobsen, D. Richman   +7 more
semanticscholar   +1 more source

Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015

Journal of Clinical Immunology, 2015
We report the updated classification of primary immunodeficiencies compiled by the Primary Immunodeficiency Expert Committee (PID EC) of the International Union of Immunological Societies (IUIS).
C. Picard, W. Al-Herz, A. Bousfiha, J. Casanova, T. Chatila, M. Conley, C. Cunningham-Rundles, Amos Etzioni, S. Holland, C. Klein, S. Nonoyama, H. Ochs, É. Oksenhendler, J. Puck, K. Sullivan, M. Tang, J. Franco, H. Gaspar   +17 more
semanticscholar   +1 more source