Results 81 to 90 of about 6,785 (163)

Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans

open access: yesViruses, 2018
The high levels of dengue-virus (DENV) seroprevalence in areas where the Zika virus (ZIKV) is circulating and the cross-reactivity between these two viruses have raised concerns on the risk of increased ZIKV disease severity for patients with a history ...
Félix G. Delgado   +6 more
doaj   +1 more source

mRNA Vaccination for Treating Allergy by Modulating Allergen‐Specific Immunity

open access: yesiLABMED, Volume 4, Issue 1, Page 56-58, March 2026.
This News and Views article discusses the rationale for anti‐allergy vaccine development using a lipid nanoparticle‐mRNA platform. The authors provide additional evidence that supports the potential of using the mRNA approach to combat allergic diseases.
Kun Guo   +4 more
wiley   +1 more source

Indirect ELISA Using Multi-Antigenic Dominants of VP1, VP2, and VP3 Recombinant Protein to Detect Antibodies Against Senecavirus A in Pigs

open access: yesVeterinary Sciences
Senecavirus A (SVA) is an emerging pathogen that poses a significant threat to the global swine industry. With the advent of SVA vaccines, there is a growing need to develop serological diagnostic methods for evaluating vaccine-induced immunity.
Zenglin Wang   +7 more
doaj   +1 more source

Morbidity and Mortality Among People Living With HTLV‐1: A 30‐Year Retrospective Analysis in a Brazilian Cohort

open access: yesJournal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT HTLV‐1 infection is a chronic condition associated with the development of malignancies, inflammatory, and neurological disorders. In this study, the causes of hospitalization and mortality were assessed in a cohort of 508 individuals living with HTLV‐1 followed over a 30‐year period. Overall mortality was 8.5% in this population and increased
Elizabeth Souza Neves   +10 more
wiley   +1 more source

Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines

open access: yesImmunology &Cell Biology, Volume 104, Issue 2, Page 150-167, February 2026.
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett   +17 more
wiley   +1 more source

Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection

open access: yesFrontiers in Immunology, 2018
Zika virus (ZIKV) has recently caused explosive outbreaks in Pacific islands, South- and Central America. Like with other flaviviruses, protective immunity is strongly dependent on potently neutralizing antibodies (Abs) directed against the viral ...
Maximilian Koblischke   +8 more
doaj   +1 more source

Evaluation of the Epitogen Lyme Detect IgG ELISA: a novel peptide multiplexing approach

open access: yesMicrobiology Spectrum
Lyme Borreliosis (LB), or Lyme disease, is a growing health concern caused by Borrelia burgdorferi sensu lato (Bbsl) bacteria transmitted through tick bites, and untreated cases can lead to severe health complications.
Tiehui Wang   +10 more
doaj   +1 more source

MHC Class II Auto-antigen Processing and Presentation is Unconventional

open access: yesFrontiers in Immunology, 2015
Antigen presentation is highly critical in adoptive immunity. Only by interacting with antigens presented by MHC Class II molecules, can helper T cells be stimulated to fight infections or diseases.
Scheherazade eSadegh-Nasseri   +1 more
doaj   +1 more source

Spatiotemporal dynamics in a model of immunodominance

open access: yes
International audienceAdapative immune response to viral infection is mediated by cytotoxic T-lymphocytes (CTLs) eliminating infected cells and virus-neutralizing antibodies produced by B-lymphocytes.
Volpert, Vitaly, Mukherjee, Nayana
core   +1 more source

Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers

open access: yesFrontiers in Immunology
Understanding adaptive immunity against SARS-CoV-2 is a major requisite for the development of effective vaccines and treatments for COVID-19. CD4+ T cells play an integral role in this process primarily by generating antiviral cytokines and providing ...
Laura Bricio-Moreno   +35 more
doaj   +1 more source

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