Results 81 to 90 of about 6,785 (163)
The high levels of dengue-virus (DENV) seroprevalence in areas where the Zika virus (ZIKV) is circulating and the cross-reactivity between these two viruses have raised concerns on the risk of increased ZIKV disease severity for patients with a history ...
Félix G. Delgado +6 more
doaj +1 more source
mRNA Vaccination for Treating Allergy by Modulating Allergen‐Specific Immunity
This News and Views article discusses the rationale for anti‐allergy vaccine development using a lipid nanoparticle‐mRNA platform. The authors provide additional evidence that supports the potential of using the mRNA approach to combat allergic diseases.
Kun Guo +4 more
wiley +1 more source
Senecavirus A (SVA) is an emerging pathogen that poses a significant threat to the global swine industry. With the advent of SVA vaccines, there is a growing need to develop serological diagnostic methods for evaluating vaccine-induced immunity.
Zenglin Wang +7 more
doaj +1 more source
ABSTRACT HTLV‐1 infection is a chronic condition associated with the development of malignancies, inflammatory, and neurological disorders. In this study, the causes of hospitalization and mortality were assessed in a cohort of 508 individuals living with HTLV‐1 followed over a 30‐year period. Overall mortality was 8.5% in this population and increased
Elizabeth Souza Neves +10 more
wiley +1 more source
Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett +17 more
wiley +1 more source
Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection
Zika virus (ZIKV) has recently caused explosive outbreaks in Pacific islands, South- and Central America. Like with other flaviviruses, protective immunity is strongly dependent on potently neutralizing antibodies (Abs) directed against the viral ...
Maximilian Koblischke +8 more
doaj +1 more source
Evaluation of the Epitogen Lyme Detect IgG ELISA: a novel peptide multiplexing approach
Lyme Borreliosis (LB), or Lyme disease, is a growing health concern caused by Borrelia burgdorferi sensu lato (Bbsl) bacteria transmitted through tick bites, and untreated cases can lead to severe health complications.
Tiehui Wang +10 more
doaj +1 more source
MHC Class II Auto-antigen Processing and Presentation is Unconventional
Antigen presentation is highly critical in adoptive immunity. Only by interacting with antigens presented by MHC Class II molecules, can helper T cells be stimulated to fight infections or diseases.
Scheherazade eSadegh-Nasseri +1 more
doaj +1 more source
Spatiotemporal dynamics in a model of immunodominance
International audienceAdapative immune response to viral infection is mediated by cytotoxic T-lymphocytes (CTLs) eliminating infected cells and virus-neutralizing antibodies produced by B-lymphocytes.
Volpert, Vitaly, Mukherjee, Nayana
core +1 more source
Understanding adaptive immunity against SARS-CoV-2 is a major requisite for the development of effective vaccines and treatments for COVID-19. CD4+ T cells play an integral role in this process primarily by generating antiviral cytokines and providing ...
Laura Bricio-Moreno +35 more
doaj +1 more source

