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The efficacy of anti-viral T-cell vaccines may greatly depend on their ability to generate high-magnitude responses targeting a broad range of different epitopes. Recently, we created the HIV T-cell immunogen HTI, designed to generate T-cell responses to
Alex Olvera +6 more
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Long term carriers were shown to generate robust polyfunctional T cell (PFC) responses against lytic and latent antigens of Epstein-Barr virus (EBV). However, the time of emergence of PFC responses against EBV antigens, pattern of immunodominance and ...
Janice K. P. Lam +5 more
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Citation: 'immunodominant epitope' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13282 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
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Design Challenges for HIV-1 Vaccines Based on Humoral Immunity
Neil S Greenspan
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B-cell epitope prediction for developing allergy vaccines and their companion immunodiagnostics
Robbi Miguel G. Falcon +3 more
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Immunodominance and tumor escape
Seminars in Cancer Biology, 2002Cancers in mouse and man express multiple tumor-specific as well as tumor-associated antigens. Immunodominance in the host response to these antigens can result in successive selection of heritable antigen loss variants. Immunodominance may also prevent the development of responses to new tumor-specific antigens that may arise during tumor progression.
H, Schreiber +3 more
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Optimal control in immunodominance
2009 First Annual ORNL Biomedical Science & Engineering Conference, 2009During the adaptive immune response, the vertebrate immune system preferentially targets a select handful of amino acid sequences, or epitopes, from hundreds that are presented by the invading pathogen. This extremely focused targeting behavior is known as immunodominance and appears to be critically important in the functioning of the adaptive immune ...
null Ruoting Yang +2 more
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The immunodominant proteins of reticuloendotheliosis virus
Veterinary Microbiology, 1996The antigenic profiles of three REV prototype strains, CSV, SNV and REV-T and eight Israeli isolates were analysed by SDS-PAGE and immunoblotting with convalescent chicken serum, three mAbs, 11A25, 11C237 and 11C100, a rabbit antiserum to REV-T whole virus (Cui et al., 1986) and a rabbit antiserum to REV-A p30 gag protein (Tsai et al., 1985).
I, Davidson +3 more
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