Results 111 to 120 of about 20,447 (254)

Cloning and structural analysis of two highly divergent IgA isotypes, IgA1 and IgA2 from the duck billed platypus, Ornithorhynchus anatinus

, 2010
To trace the emergence of modern IgA isotypes during vertebrate evolution we have studied the immunoglobulin repertoire of a model monotreme, the platypus.
K. Belov, M. Aveskogh, L. Hellman, Vernersson, Molly,, M. Vernersson, Aveskogh, Maria,, Hellman, Lars,, Belov, K.   +7 more
core   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life. [PDF]

, 2007
BACKGROUND: Data suggest that antibody responses to malaria parasites merozoite antigens are generally short-lived and this has implications for serological studies and malaria vaccine designs.
Conway, David J, Conway David J, Marsh Kevin, Kevin Marsh, Marsh, K, Lanar David E, Conway, DJ, Kinyanjui, Samson M, Lanar, David E, Lanar, DE, David E Lanar, David J Conway, Kinyanjui Samson M, Kinyanjui, SM, Marsh, Kevin, Samson M Kinyanjui   +15 more
core   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis [PDF]

, 2016
Background: The presence of rheumatoid factor (RF), anti-carbamylated protein antibodies (anti-CarP) and antibodies against citrullinated protein and peptides (ACPA) precedes the onset of symptoms of rheumatoid arthritis (RA) by several years ...
Klareskog, Lars, Trouw, Leendert A., Rikard Holmdahl, Lars Klareskog, Verheul, M.K., Mathsson-Alm, L., Trouw, L.A., Klareskog, L., Hansson, M., Mikael Brink, Rönnelid, Johan, Brink, Mikael, Wijayatunga, Priyantha,, Priyantha Wijayatunga, Holmdahl, R., Wijayatunga, Priyantha, Linda Mathsson-Alm, Holmdahl, Rikard, Verheul, Marije K., Holmdahl, R, Johan Rönnelid, Monika Hansson, Leendert A. Trouw, Rantapää-Dahlqvist, Solbritt,, Marije K. Verheul, Trouw, L.A, Mathsson-Alm, Linda, Rantapaa-Dahlqvist, S., Rönnelid, J., Wijayatunga, P., Brink, Mikael,, Hansson, M, Brink, M., Solbritt Rantapää-Dahlqvist, Rantapaa-Dahlqvist, Solbritt, Mathsson-Alm, L, Hansson, Monika, Verheul, M.K   +37 more
core   +1 more source

Cytokine and Antibody Isotype Responses in Vaccinated Healthcare Workers with SARS-CoV-2 Breakthrough Infections

Viruses
Background: Healthcare workers (HCWs) are at high risk of breakthrough SARS-CoV-2 infections despite complete vaccination schedules. There are gaps in our understanding of the specific antibody isotypes and cytokine profiles produced during an infection ...
Miguel Ángel Fernández-Rojas, Tanya Plett-Torres, Guillermina Ávila, Mirza Romero-Valdovinos, Ana María Salazar, Monserrat Sordo, Mariana Chávez-Vargas, Cesar Josué Coeto Ángeles, Mayra Cruz-Rivera, Carlos Santiago-Olivares, Juan Pablo Ramírez Hinojosa, Pablo Maravilla, Patricia Ostrosky-Wegman, Fela Mendlovic, Ana Flisser   +14 more
doaj   +1 more source

Adjuvant Injections Altered the Ileal and Fecal Microbiota Differently with Changes in Immunoglobulin Isotypes and Antimycobacterial Antibody Responses. [PDF]

Int J Mol Sci, 2023
Khadka S, Omura S, Sato F, Tsunoda I.
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Complications of untreated hypogammaglobulinemia in a patient with common variable immunodeficiency – A case report

International Journal of Immunopathology and Pharmacology
Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by decreased or undetectable serum levels of immunoglobulin G (IgG), decreased levels of IgA isotypes, and poor specific antibody production in response to ...
Kinga Grochowalska, Marcin Ziętkiewicz, Jarosław Dulski, Jarosław Sławek, Hanna Suchanek, Marta Jaskólska   +5 more
doaj   +1 more source

Levels of immunoglobulin isotypes in serum and respiratory samples of patients with chronic obstructive pulmonary disease: protocol for a systematic review and meta-analysis. [PDF]

BMJ Open, 2023
Unninayar D, Shea B, Cameron DW, Cowan J.   +3 more
europepmc   +1 more source