Results 121 to 130 of about 478,815 (317)

Comparative Detection of Immunoglobulin Isotypes and Subclasses against Toxoplasma gondii Soluble Antigen in Serum and Colostrum Samples from Puerperal Women. [PDF]

Int J Environ Res Public Health, 2022
Borges HDS, Oliveira-Scussel ACM, Oliveira ÂMM, Abdallah VOS, Pajuaba ACAM, Mineo JR.   +5 more
europepmc   +1 more source

SERPINB9 Promotes Colorectal Cancer Liver Metastasis and Immunotherapy Resistance: Association With MHC‐I Downregulation and CD8+ T Cell Dysfunction

Medicine Bulletin, EarlyView.
ABSTRACT Background Colorectal cancer liver metastasis (CRLM) is the leading cause of mortality in colorectal cancer (CRC) patients, for which effective treatments remain limited. The mechanisms by which tumor cells evade immune surveillance and escape cytotoxic killing remain poorly understood.
Xin Liu, Wenchen Wang, Hongqian Wang, Yanshen Kuang, Baoqing Jia   +4 more
wiley   +1 more source

Performance estimation of two in-house ELISA assays for COVID-19 surveillance through the combined detection of anti-SARS-CoV-2 IgA, IgM, and IgG immunoglobulin isotypes. [PDF]

PLoS One, 2023
Ramírez-Reveco A, Velásquez G, Aros C, Navarrete G, Villarroel-Espíndola F, Navarrete M, Fica A, Plaza A, Castro N, Verdugo C, Acosta-Jamett G, Verdugo CC.   +11 more
europepmc   +1 more source

Cytokine and Antibody Isotype Responses in Vaccinated Healthcare Workers with SARS-CoV-2 Breakthrough Infections

Viruses
Background: Healthcare workers (HCWs) are at high risk of breakthrough SARS-CoV-2 infections despite complete vaccination schedules. There are gaps in our understanding of the specific antibody isotypes and cytokine profiles produced during an infection ...
Miguel Ángel Fernández-Rojas, Tanya Plett-Torres, Guillermina Ávila, Mirza Romero-Valdovinos, Ana María Salazar, Monserrat Sordo, Mariana Chávez-Vargas, Cesar Josué Coeto Ángeles, Mayra Cruz-Rivera, Carlos Santiago-Olivares, Juan Pablo Ramírez Hinojosa, Pablo Maravilla, Patricia Ostrosky-Wegman, Fela Mendlovic, Ana Flisser   +14 more
doaj   +1 more source

IL-4 and transforming growth factor-β suppress human immunoglobulin secretion in vitro by surface IgD− B cells

, 1992
SUMMARY The effect of IL-4 and transforming growth factor-β (TGF-β) on immunogiobulin secretion in vitro by peripheral blood mononuclear cells (PBMC) or purified B cells activated with murine EL4 thymoma cells and phorbol myristate acetate
C NINOMIYA, H L SPIEGELBERG
core   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Distribution of immunoglobuline isotypes and salmonella antibodies in blood serum and meat juice of pigs

, 2003
Using the close linear regression between the logarithm of the dilution degree of a sample and the logarithm of the extinction measured in an ELISA both the relative concentrations of immunoglobulines of the isotypes IgG, IgM and IgA and of the LPS ...
Steinbach, G., Methner, Ulrich, Meyer, H.   +2 more
core  

Identification of Active Compounds of Centipeda minima for Potentiating Tumor Immunotherapy in Non‐Small Cell Lung Cancer via FANCD2‐cGAS/STING/IFN‐I Signaling Axis

Phytotherapy Research, EarlyView.
Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang, Chu‐Ying Chen, Jiang‐Tao Xiao, Rou‐Qiao Zheng, Wen‐Da He, Zi‐Wei Xu, Su‐Fen Wei, Tao Su, Guang‐Biao Zhou, Yong‐Qiang Liu   +9 more
wiley   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Distinct kinetics of immunoglobulin isotypes reveal early diagnosis and disease severity of COVID-19: A 6-month follow-up. [PDF]

Clin Transl Med, 2021
Yu S, An J, Liao X, Wang H, Ma F, Li D, Li A, Liu W, Zhang S, Liao M, Liu L, Zhao J, Xing S, Wei L, Zhang Z.   +14 more
europepmc   +1 more source