Results 41 to 50 of about 74,618 (225)

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Cerebrospinal Fluid Immunoglobulin Kappa Light Chain in Clinically Isolated Syndrome and Multiple Sclerosis

PLoS ONE, 2014
Background Oligoclonal bands (OCB) are the most widely used CSF test to support the diagnosis of MS and to predict conversion of clinically isolated syndrome (CIS) to multiple sclerosis (MS). Since OCB tests are based on non-quantitative and difficult to
M. Senel, H. Tumani, F. Lauda, S. Presslauer, Rehaneh Mojib-Yezdani, M. Otto, J. Brettschneider   +6 more
semanticscholar   +1 more source

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Striking Bone Marrow Plasmacytosis Resulting From Visceral Leishmaniasis

American Journal of Hematology, EarlyView.
Vishakha Sovani, Jennifer Ryan, Barbara J. Bain   +2 more
wiley   +1 more source

Dual‐Field Synergistic Orientation of Carbon Fibers for High‐Efficiency Thermal Management

Carbon Energy, EarlyView.
The sample fabricated by synergistically combining reversed electric and low magnetic fields, with photocurable PEG/PPG gel serving as the matrix, exhibits excellent machinability and flexibility. Meanwhile, the thermal conductivity enhancement efficiency of this work is 1351%, significantly superior to similar carbon fiber composite materials ...
Zujian Zhao, Kang Xu, Yue Qin, Boren Yang, Kaiyuan Li, Linhong Li, Rongjie Yang, Yandong Wang, Hanxi Chen, Yiwei Zhou, Tao Cai, Cheng‐Te Lin, Kazuhito Nishimura, Maohua Li, Nan Jiang, Jinhong Yu   +15 more
wiley   +1 more source

CO2‐Driven Synthesis of Holey Edge‐Carboxylated Graphene for Tunable Electronic Interactions in Cu–CeO2‐Catalyzed Water‐Gas Shift Reaction

Carbon Energy, EarlyView.
Holey‐structured, edge‐carboxylated graphene with a controlled specific surface area was synthesized using an environmentally friendly, CO2‐activated, KOH‐free ball‐milling process. ABSTRACT Graphene, notable for its high specific surface area, is ideal for catalyst support but faces challenges under harsh thermal catalytic conditions.
Seon‐Yong Ahn, I‐Jeong Jeon, Won‐Jun Jang, In‐Yup Jeon, Jae‐Oh Shim, Hyun‐Seog Roh   +5 more
wiley   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Unusual patterns of immunoglobulin gene rearrangement and expression during human B cell ontogeny: human B cells can simultaneously express cell surface kappa and lambda light chains

Journal of Experimental Medicine, 1993
Immunoglobulin gene rearrangement during mammalian B cell development generally follows an ordered progression, beginning with heavy (H) chain genes and proceeding through kappa and lambda light (L) chain genes. To determine whether the predicted kappa-->
M. Pauza, J. A. Rehmann, T. Lebien
semanticscholar   +1 more source