Results 31 to 40 of about 765,793 (291)
Simultaneous tubular and glomerular involvement with cryoglobulinemia vasculitis in multiple myeloma
Saudi Journal of Kidney Diseases and Transplantation, 2019 Renal manifestations in myeloma are varied. Tubulopathic light chains cause cast nephropathy or proximal tubulopathy, usually associated with tubulointerstitial nephritis.
Zafirah Zahir +3 more
doaj +1 more source
Biomarker Research, 2023 Light chain amyloidosis (AL) is a rare disease caused by the generalized deposition of misfolded free light chains. Patients with immunoglobulin M gammopathy (IgM) and indolent B-cell lymphoma such as marginal zone lymphoma (MZL) may in some instances ...
Felix Korell +8 more
doaj +1 more source
Медицинская иммунология, 2015 Increased intrathecal synthesis and oligoclonal banding of immunoglobulins (Ig) in cerebrospinal fluid (CSF) are major immunological findings in multiple sclerosis.
V. D. Nazarov +5 more
doaj +1 more source
Transposition of two different intracisternal A particle elements into an immunoglobulin kappa-chain gene. [PDF]
Molecular and Cellular Biology, 1984 Each of two severely defective mouse kappa-chain genes has acquired a different intracisternal A particle (IAP) element within one of its introns. One IAP element generated 6-base-pair direct repeats upon insertion. In contrast, the other IAP element was not flanked by direct repeats and was missing a single nucleotide from its 3' terminus.
R G, Hawley, M J, Shulman, N, Hozumi
openaire +2 more sources
The disulphide bridges of immunoglobulin ϰ-chains [PDF]
Biochemical Journal, 1966 The arrangement of the disulphide bridges of the major component of the light chains of immunoglobulins (kappa-chains) has been studied in the Bence-Jones proteins. Three disulphide bridges have been found. An interchain bridge at the C-terminus has been shown to occur in the dimers of all the proteins studied and was characterized by symmetrical ...
openaire +2 more sources
IGK@ (immunoglobulin kappa) [PDF]
, 2003 Review on IGK@ (immunoglobulin kappa), with data on DNA, on the protein encoded, and where the gene is ...
MP Lefranc, Lefranc, MP
core +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2015 Light chain deposition disease (LCDD) is characterized by the tissue deposition of monotypic immunoglobulin light chains of either kappa or lambda isotype.
Sihem Darouich +6 more
doaj +1 more source
Sequences related to immunoglobulin kappa chain messenger RNA in T cells. [PDF]
Proceedings of the National Academy of Sciences, 1976 We investigated by molecular hybridization whether T cells contain RNA sequences homologous to RNA which codes for immunoglobulin kappa-chain (k-chain). A radioactive probe of complementary DNA (cDNA) was prepared by transcription of purified k-chain mRNA from mouse myeloma MOPC-41 with reverse transcriptase (RNA-dependent-DNA nucleotidyltransferase ...
U, Storb +5 more
openaire +2 more sources
Targeting Inflammation in the Diagnosis, Management, and Prevention of Cardiovascular Diseases
Global Heart, 2022 Inflammation plays an important role in the development and progression of cardiovascular diseases (CVDs). Hypertension and hyperlipidemia are the key risk factors of CVDs and induce inflammation in the heart and vessels.
Akira Matsumori
doaj +1 more source
DNA sequence of the constant gene region of the mouse immunoglobulin kappa chain
Nucleic Acids Research, 1981 The constant (C; ref. 3) gene segment of the immunoglobulin kappa light chain and about 1 kb upstream as well as downstream of the segment have been sequenced. The sequences of the C gene segment itself and parts of the upstream region were determined both in liver and in myeloma T DNA clones derived from the same mouse inbred strain.
W, Altenburger +3 more
openaire +3 more sources