To substitute or not? A systematic review of immunoglobulin replacement therapy in multiple myeloma patients treated with bispecific antibodies [PDF]
Frontiers in ImmunologyBispecific antibodies are a novel class of immunotherapies that have demonstrated high response rates in heavily pretreated patients with multiple myeloma.
Juni Songe Paulsen +4 more
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Cytokine dysregulation despite immunoglobulin replacement therapy in common variable immunodeficiency (CVID) [PDF]
Frontiers in Immunology, 2023 IntroductionCommon variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. CVID is a heterogeneous disorder with a presumed multifactorial etiology. Intravenous or subcutaneous immunoglobulin replacement therapy (IgRT)
Remo Poto +24 more
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Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review [PDF]
Allergy, Asthma & Clinical ImmunologyPurpose Immunoglobulin replacement therapy is a standard treatment for patients with antibody production deficiencies, which is of interest in patients with chronic obstructive pulmonary disease (COPD).
Justin J. Y. Kim +5 more
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Use of Immunoglobulin Replacement Therapy in Clinical Practice: A Review [PDF]
Journal of Immunotherapy and Precision OncologyImmunoglobulins (Igs) are produced by B lymphocytes and play a key role in humoral immunity. Igs are classified into five isotypes (IgG, IgA, IgM, IgE, and IgD). Their primary function is to recognize and bind to foreign antigens.
Jibran Ahmed +4 more
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Current Practice and Perspectives on Subcutaneous Immunoglobulin Replacement Therapy in Patients with Primary Antibody Deficiency Among Specialized Nurses in Poland [PDF]
Nursing ReportsBackground/Objectives: Inborn errors of immunity (IEI) encompass various congenital disorders, resulting in immunity defects and recurrent infections. Home-based subcutaneous immunoglobulin replacement therapy (scIgRT) is the best treatment option for ...
Dorota Mizera +7 more
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A clinician’s guide for administration of high-concentration and facilitated subcutaneous immunoglobulin replacement therapy in patients with primary immunodeficiency diseases [PDF]
Allergy, Asthma & Clinical Immunology, 2022 Immunoglobulin replacement therapy is the standard-of-care treatment for patients with primary immunodeficiency diseases who have impaired antibody production and function.
Kristin Epland +2 more
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Facilitated Subcutaneous Immunoglobulin Replacement Therapy in Clinical Practice: A Two Center, Long-Term Retrospective Observation in Adults With Primary Immunodeficiencies [PDF]
Frontiers in Immunology, 2020 Facilitated subcutaneous immunoglobulin (fSCIG) replacement therapy is the latest method of IgG administration; however, real-life data are limited. We retrospectively analyzed the everyday experience of fSCIG administration, particularly, the method ...
Ewa Wiesik-Szewczyk +4 more
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Immunoglobulin Replacement Therapy for Hypogammaglobulinemia in Multiple Myeloma Should Not Be Ignored [PDF]
Turkish Journal of HematologyQinggang Zhang, Yongliang Wang, Wei Pan
doaj +2 more sources
Frontiers in Oncology, 2023 Chronic lymphocytic leukaemia (CLL) is a malignancy of clonally expanded antigen-switched, neoplastic, mature B cells. CLL is characterised by a variable degree of immunosuppression and secondary hypogammaglobulinemia.
Sujoy Khan +3 more
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Trends in Pediatrics, 2023 Objective: In a large group of patients with primary immunodeficiency (PID), immunoglobulin replacement therapy is critical for infection control. There are two main methods of immunoglobulin replacement intravenous (IVIG) and subcutaneous (SCIG).
Selime Özen Bölük +9 more
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