Results 31 to 40 of about 326,951 (318)

Clinical significance of LAIR1 (CD305) as assessed by flow cytometry in a prospective series of patients with chronic lymphocytic leukemia

Haematologica, 2014
Most patients affected by chronic lymphocytic leukemia are diagnosed by flow cytometry. Several immunophenotypic markers have been identified as significant and independent prognostic variables, especially from retrospective cohorts.
Omar Perbellini, Erika Falisi, Ilaria Giaretta, Elisa Boscaro, Elisabetta Novella, Monica Facco, Stefania Fortuna, Silvia Finotto, Eliana Amati, Francesco Maniscalco, Anna Montaldi, Alberta Alghisi, Fiorenza Aprili, Laura Bonaldi, Rossella Paolini, Maria Teresa Scupoli, Livio Trentin, Achille Ambrosetti, Gianpietro Semenzato, Giovanni Pizzolo, Francesco Rodeghiero, Carlo Visco   +21 more
doaj   +1 more source

Immunoglobulin genes and diversity: what we have learned from domestic animals

Journal of Animal Science and Biotechnology, 2012
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi, Liu Zhancai, Ren Liming, Wei Zhiguo, Wang Ping, Li Ning, Zhao Yaofeng   +6 more
doaj   +1 more source

Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

Journal of Experimental Medicine, 1998
Immunoglobulin (Ig)M+IgD+ B cells are generally assumed to represent antigen-inexperienced, naive B cells expressing variable (V) region genes without somatic mutations. We report here that human IgM+IgD+ peripheral blood (PB) B cells expressing the CD27
U. Klein, K. Rajewsky, R. Küppers
semanticscholar   +1 more source

A novel liver-specific immunoglobulin heavy chain-like gene in a cartilaginous fish

Fish and Shellfish Immunology Reports, 2023
We identified a novel immunoglobulin (Ig) heavy chain-like gene (tsIgH) expressed in the liver of the banded houndshark Triakis scyllium by preliminary transcriptomic analysis.
Hidehiro Kondo, Haruka Kamei, Fuyuka Murotani, Reiko Nozaki, Ryosuke Yazawa, Reoto Tani, Keiichiro Koiwai, Ikuo Hirono   +7 more
doaj   +1 more source

White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia

Haematologica, 2011
A comprehensive panel of clinical-biological parameters was prospectively evaluated at presentation in 112 patients with chronic lymphocytic leukemia (
I. Del Giudice, F. Mauro, M. D. De Propris, S. Santangelo, M. Marinelli, N. Peragine, V. Di Maio, M. Nanni, R. Barzotti, F. Mancini, D. Armiento, F. Paoloni, A. Guarini, R. Foà   +13 more
semanticscholar   +1 more source

Tumor-Associated Disialylated Glycosphingolipid Antigen-Revealing Antibodies Found in Melanoma Patients' Immunoglobulin Repertoire Suggest a Two-Direction Regulation Mechanism Between Immune B Cells and the Tumor

Frontiers in Immunology, 2019
There is far less information available about the tumor infiltrating B (TIL-B) cells, than about the tumor infiltrating T cells. We focused on discovering the features and potential role of B lymphocytes in solid tumors.
Beatrix Kotlan, Szabolcs Horvath, Klara Eles, Vanda K. Plotar, Gyorgy Naszados, Katalin Czirbesz, Miri Blank, Emil Farkas, Laszlo Toth, Jozsef Tovari, Andras Szekacs, Yehuda Shoenfeld, Maria Godeny, Miklos Kasler, Miklos Kasler, Gabriella Liszkay   +15 more
doaj   +1 more source

Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains

Data in Brief, 2018
The highly variable complementary determining region 3 (CDR3) of antibodies is generated through recombination of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes.
Linnea Thörnqvist, Mats Ohlin
doaj   +1 more source

Big domains are novel Ca²+-binding modules: evidences from big domains of Leptospira immunoglobulin-like (Lig) proteins. [PDF]

PLoS ONE, 2010
BackgroundMany bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig) proteins, LigA and LigB, are surface exposed proteins containing Bacterial ...
Rajeev Raman, V Rajanikanth, Raghavan U M Palaniappan, Yi-Pin Lin, Hongxuan He, Sean P McDonough, Yogendra Sharma, Yung-Fu Chang   +7 more
doaj   +1 more source

Immunodeficiency, Centromeric Region Instability, and Facial Anomalies Syndrome (ICF) in a Boy with Variable Clinical and Immunological Presentations

Iranian Journal of Allergy, Asthma and Immunology, 2021
Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a rare primary immunodeficiency disorder characterized by recurrent infections and low immunoglobulin levels due to variable combined immunodeficiency, and centromeric ...
Mohammad Hassan Bemanian, Saba Arshi, Mohammad Nabavi, Mohammad Vafaee-Shahi, Morteza Fallahpour, Sima Shokri, Afshin Rezaeifar, Hossein Shahzadi, Fatemeh Atashrazm   +8 more
doaj   +1 more source

A genome-wide association study for allergen component sensitizations identifies allergen component–specific and allergen protein group–specific associations

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Allergic diseases are some of the most common diseases worldwide. Genome-wide association studies (GWASs) have been conducted to elucidate the genetic factors of allergic diseases.
Wataru Morii, PhD, Koki Kasai, BS, Takako Nakamura, MSc, Daisuke Hayashi, MD, Monami Hara, MD, Tatsuhiko Naito, MD, PhD, Kyuto Sonehara, MD, PhD, Tatsuki Fukuie, MD, PhD, Mayako Saito-Abe, MD, PhD, Limin Yang, MD, PhD, Kiwako Yamamoto-Hanada, MD, PhD, Masami Narita, MD, PhD, Kazushi Maruo, PhD, Yukinori Okada, MD, PhD, Emiko Noguchi, MD, PhD, Yukihiro Ohya, MD, PhD   +15 more
doaj   +1 more source