A Low-temperature 1H NMR Study of H2O and D2O Associated Competitively with Immunoglobulin G in Solution [PDF]
arXiv, 2007 An approach has been proposed to characterize the competitive association of D2O and to study the heterogeneity of hydration water adsorbed by the protein, immunoglobulin G, using methodology for determining of non-freezing water in mixed H2O-D2O protein solutions by low-temperature 1H NMR technique. Direct data on the numbers of deuteriums adsorbed by
arxiv
Molecular Medicine, 2013 Chronic lymphocytic leukemia (CLL) is a clonal disease of a subset of human B lymphocytes. Although the cause of the disease is unknown, its development and evolution appear to be promoted by signals delivered when B-cell receptors (BCRs) engage (auto ...
Yun Liu +5 more
doaj +1 more source
Dynamic model of HIV infection with immune system response of T-lymphocytes, B-cells and dendritic cells: a review [PDF]
arXiv, 2020 A dynamic model of non-lineal time-dependent ordinary differential equations (ODE) has been applied to the interactions of a HIV infection with the immune system cells. This model has been simplified into two compartments: lymph node and peripheral blood.
arxiv
Study on Antibody-Virus Interaction using Molecular Dynamics: Two Dimensional Simulation on Immunoglobulin Reaction against Human Papillomavirus [PDF]
arXiv, 2013 Human Papillomavirus (HPV) has been known as one of the cause of virus-induced cancer such as cervical cancer and carcinoma. Among other types of cancer, this type has higher chance in being prevented earlier. The main idea is to eradicate the virus as soon as it enters the body by marking it with antibodies; signaling the immune system to dispose of ...
arxiv
Virulence, 2018 Background: Staphylococcus pseudintermedius is an opportunistic pathogen that is the major cause of pyoderma affecting dogs. Conventional antimicrobial treatment for infections caused by this organism have failed in recent years due to widespread ...
Mohamed A. Abouelkhair +2 more
doaj +1 more source
Emergence of clonal selection and affinity maturation in an ab initio microscopic model of immunity [PDF]
arXiv, 2007 Mechanisms of immunity, and of the host-pathogen interactions in general are among the most fundamental problems of medicine, ecology, and evolution studies. Here, we present a microscopic, protein-level, sequence-based model of immune system, with explicitly defined interactions between host and pathogen proteins..
arxiv
Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis. [PDF]
, 1978 Jonathan G. Seidman +6 more
openalex +1 more source
A Genetic Marker in the Variable Region of Light Chains of Mouse Immunoglobulins [PDF]
, 1970 Gerald M. Edelman, Paul Gottlieb
openalex +1 more source
Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish
iScience, 2021 Summary: B cells express a unique antibody protein which comprises two pairs of immunoglobulin (Ig) heavy (H) and light (L) chains. In addition to an invariable constant (C) region, IgH and IgL chains encompass a variable (V) region mediating antigen ...
Pedro Perdiguero +3 more
doaj
Frontiers in Immunology, 2017 B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes.
Nurit Hollander, Joseph Haimovich
doaj +1 more source