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Allergic and immunologic evaluation of children with celiac disease [PDF]
Frontiers in PediatricsIntroductionCeliac disease (CD) and allergic diseases are immune-mediated disorders with overlapping clinical and immunologic features. The association between CD and selective immunoglobulin (Ig) A deficiency (sIgAD) is well-established, but limited ...
Duygu Demirtaş Güner, Kübra Baskın
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The intersection of COVID-19 and autoimmunity: What is our current understanding?
Pathogens and Immunity, 2021 Viral infections have historically had a complex relationship with autoimmune diseases. For patients with preexisting autoimmune disorders, often complicated by immunosuppressive therapies, there are numerous potential effects of COVID-19, a disease of ...
Nicole Eve Winchester +2 more
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PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis
Nature Communications, 2021 Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell ...
Thais G. Moreira +18 more
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Clinical and Applied Thrombosis/Hemostasis, 2022 Background Thrombotic antiphospholipid syndrome (APS) is a systemic autoimmune disease; its diagnosis requires meeting both clinical and laboratory criteria.
Zhenzhen Su MM +7 more
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iScience, 2021 Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimulate ...
Galina Gabriely +17 more
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Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases
Frontiers in Immunology, 2021 Protein S-palmitoylation is a covalent and reversible lipid modification that specifically targets cysteine residues within many eukaryotic proteins. In mammalian cells, the ubiquitous palmitoyltransferases (PATs) and serine hydrolases, including acyl ...
Yuqi Zhang +4 more
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Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis [PDF]
PeerJ, 2020 Background Juvenile dermatomyositis (JDM) is an immune-mediated disease characterized by chronic organ inflammation. The pathogenic mechanisms remain ill-defined.
Danli Zhong +5 more
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Chinese Expert Consensus on Juvenile Idiopathic Arthritis-associated Uveitis (2023)
Xiehe Yixue Zazhi, 2023 Juvenile idiopathic arthritis (JIA) is a common chronic rheumatologic disease in childhood. JIA-associated uveitis (JIA-U), an important extra-articular complication of JIA, is one of the major causes of childhood disability and blindness.
The Subspecialty Group of Immunology, the Society of Pediatrics, Chinese Medical Association +2 more
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Arthritis Research & Therapy, 2020 Backgrounds Despite the advances of rheumatoid arthritis (RA) therapeutics, several patients do not receive adequate treatment due to the toxicity and/or insufficient response of drugs.
You-Jung Ha +9 more
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Acta Dermato-Venereologica, 2023 Hypopigmented mycosis fungoides is a rare form of mycosis fungoides that is characterized by achromic lesions, early onset of disease, a predilection for darker skinned populations, and a predominance of CD8+ T cells.
Zhong-Hui Hu +7 more
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