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Immunology and Immunologic Diseases of the Lung [PDF]

JAMA: The Journal of the American Medical Association, 1989
ABSTRACT Immunology and Immunologic Diseases of the Lung, edited by Ronald P. Daniele, MD, is an important addition to the many books on pulmonary medicine. The explosive growth of knowledge in immunology during the past few decades and the recognition that the lung is a key player in many immunologic disorders justify the assembly of this material as ...

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A 5-week low-dose prednisolone regimen for progressive vitiligo: efficacy and safety in a single-center cohort study [PDF]

Annals of Medicine
Background Progressive vitiligo lacks standardized glucocorticoid regimens, with prolonged treatments often causing adverse effects. This study evaluated a novel 5-week low-dose prednisolone strategy (0.5 mg/kg/day, tapered weekly) to balance efficacy ...
Yue-Tong Qian, Jia-Wei Liu, Dong-Lai Ma
doaj   +2 more sources

The intersection of COVID-19 and autoimmunity: What is our current understanding?

Pathogens and Immunity, 2021
Viral infections have historically had a complex relationship with autoimmune diseases. For patients with preexisting autoimmune disorders, often complicated by immunosuppressive therapies, there are numerous potential effects of COVID-19, a disease of ...
Nicole Eve Winchester, Cassandra Calabrese, Leonard Calabrese   +2 more
doaj   +1 more source

T Cells Immunology in the Immunological Diseases [PDF]

Journal of Immunology Research, 2014
Immunological diseases, with the morbidity keeping increased, have become a major threat to human mental and physical health. However, the pathogenesis of these diseases is extremely complicated and remains unclear. Recent advances in biology have introduced new technologies to study the underlying mechanisms that contribute to the development of ...
Qifa Liu, Grzegorz K. Przybylski, Xiuli Wu, Qintai Yang   +3 more
openaire   +3 more sources

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis

Nature Communications, 2021
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell ...
Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner   +18 more
doaj   +1 more source

Detection of IgA Antiphospholipid Antibodies Does not Improve Thrombotic Antiphospholipid Syndrome Classification: A two-Center Study

Clinical and Applied Thrombosis/Hemostasis, 2022
Background Thrombotic antiphospholipid syndrome (APS) is a systemic autoimmune disease; its diagnosis requires meeting both clinical and laboratory criteria.
Zhenzhen Su MM, Zhuochun Huang MD, Jiuliang Zhao MD, Mengtao Li MD, Jing Hu BS, Xiaofeng Zeng MD, Chaojun Hu PhD, Bin Yang PhD   +7 more
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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

iScience, 2021
Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimulate ...
Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou-El-Hassan, Thais G. Moreira, Dustin Donnelly, Andre P. da Cunha, Mai Fujiwara, Lena R. Walton, Amee Patel, Rajesh Krishnan, Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner   +17 more
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Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases

Frontiers in Immunology, 2021
Protein S-palmitoylation is a covalent and reversible lipid modification that specifically targets cysteine residues within many eukaryotic proteins. In mammalian cells, the ubiquitous palmitoyltransferases (PATs) and serine hydrolases, including acyl ...
Yuqi Zhang, Ziran Qin, Wenhuan Sun, Feng Chu, Fangfang Zhou   +4 more
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Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis [PDF]

PeerJ, 2020
Background Juvenile dermatomyositis (JDM) is an immune-mediated disease characterized by chronic organ inflammation. The pathogenic mechanisms remain ill-defined.
Danli Zhong, Chanyuan Wu, Jingjing Bai, Dong Xu, Xiaofeng Zeng, Qian Wang   +5 more
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Chinese Expert Consensus on Juvenile Idiopathic Arthritis-associated Uveitis (2023)

Xiehe Yixue Zazhi, 2023
Juvenile idiopathic arthritis (JIA) is a common chronic rheumatologic disease in childhood. JIA-associated uveitis (JIA-U), an important extra-articular complication of JIA, is one of the major causes of childhood disability and blindness.
The Subspecialty Group of Immunology, the Society of Pediatrics, Chinese Medical Association, Chinese Alliance of Pediatric Rheumatic and Immunologic Diseases, Alliance of Rheumatic and Immunologic Diseases, National Clinical Research Center for Child Health and Disorders   +2 more
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