Results 101 to 110 of about 19,457 (207)

ICAM-1 enhances MHC-peptide activation of CD8+ T cells without an organized immunological synapse [PDF]

, 2000
Julia Goldstein, Trina Chen, Elena Gubina, Richard W. Pastor, Steven Kozlowski   +4 more
openalex   +1 more source

Comparative anatomy of phagocytic and immunological synapses

Frontiers in Immunology, 2016
The generation of phagocytic cups and immunological synapses are crucial events of the innate and adaptive immune responses, respectively. They are triggered by distinct immune receptors and performed by different cell types.
Florence eNiedergang, Vincenzo eDi Bartolo, Andres eAlcover   +2 more
doaj   +1 more source

An introduction to the immune network [PDF]

arXiv, 1995
In this paper, after a telegraphic introduction to modern immunology, we present a simple model for the idiotypic network among antibodies and we study its relevance for the maintenance of immunological memory. We also consider the problem of computing the memory capacity of such a model.
arxiv  

Cutting Edge: The Dendritic Cell Cytoskeleton Is Critical for the Formation of the Immunological Synapse [PDF]

, 2001
Monther Al‐Alwan, Geoffrey Rowden, Timothy D.G. Lee, Kenneth A. West   +3 more
openalex   +1 more source

Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

Exploration, EarlyView.
Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao, Juanjuan Li, Yanming Ma, Min Xie, Jianxian Luo, Ke Wang, Cheng Peng, Hua Yang, Tianjun Chen, Guowei Zhang, Jiang Ouyang, Hongsheng Lin, Zhisheng Ji   +12 more
wiley   +1 more source

The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse

Frontiers in Cell and Developmental Biology, 2018
The immunological synapse (IS) is a specialized structure that serves as a platform for cell-cell communication between a T cell and an antigen-presenting cell (APC).
Nathan H. Roy, Janis K. Burkhardt, Janis K. Burkhardt   +2 more
doaj   +1 more source

Shannon Information Capacity of Discrete Synapses [PDF]

arXiv, 2008
There is evidence that biological synapses have only a fixed number of discrete weight states. Memory storage with such synapses behaves quite differently from synapses with unbounded, continuous weights as old memories are automatically overwritten by new memories.
arxiv  

Mac-1 (CD11b/CD18) is essential for Fc receptor–mediated neutrophil cytotoxicity and immunologic synapse formation [PDF]

, 2001
Annemiek B. van Spriel, Jeanette H.W. Leusen, Marjolein van Egmond, Henry Dijkman, Karel J.M. Assmann, Tanya N. Mayadas, Jan G. J. van de Winkel   +6 more
openalex   +1 more source

Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells

Frontiers in Immunology, 2013
Upon engagement of their cognate class I major histocompatibility complex (MHC) ligands, receptors containing immunotyrosine-based inhibitory motifs (ITIMs) transduce signals that block cytolytic and inflammatory responses.
Thushara P Abeyweera, Morgan eHuse, Molly eKaissar   +2 more
doaj   +1 more source

Population dynamics of immunological synapse formation induced by bispecific T cell engagers predict clinical pharmacodynamics and treatment resistance. [PDF]

Elife, 2023
Liu C, Zhou J, Kudlacek S, Qi T, Dunlap T, Cao Y.   +5 more
europepmc   +1 more source