The immunological synapse: a cause or consequence of T-cell receptor triggering?
Balbino Alarcón +2 more
openalex +2 more sources
Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov +10 more
wiley +1 more source
Ganglioside-Functionalized Nanoparticles for Chimeric Antigen Receptor T-Cell Activation at the Immunological Synapse. [PDF]
Zang H +4 more
europepmc +1 more source
Tocotrienols: A Review From Source to Therapeutic Applications
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño +6 more
wiley +1 more source
The Immunological Synapse: An Emerging Target for Immune Evasion by Bacterial Pathogens. [PDF]
Capitani N, Baldari CT.
europepmc +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse. [PDF]
Kvalvaag A +6 more
europepmc +1 more source
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen +10 more
wiley +1 more source
Transcriptional and post-transcriptional regulation of checkpoint genes on the tumour side of the immunological synapse. [PDF]
Dobosz P +3 more
europepmc +1 more source

