Results 151 to 160 of about 226,715 (279)
Minutes of the 58th meeting of the Council of the International Union of Immunological Societies
, 2011 Meeting minutes of the 58th meeting of the Council of the International Union of Immunological Societies held on June 23rd, 2011 in Washington, D.C ...
International Union of Immunological Societies
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Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy
Epilepsia, EarlyView.Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber +13 more
wiley +1 more source
The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity
Epilepsia Open, EarlyView.Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia +4 more
wiley +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen +10 more
wiley +1 more source
CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse. [PDF]
Front Immunol, 2022 Molon B, Liboni C, Viola A.
europepmc +1 more source
Ibrain, EarlyView.Exosome therapy shows promise in Alzheimer's disease. This study compared normal and modified exosomes from AD brain extract‐treated MSCs in STZ‐induced SH‐SY5Y cells. Exosomes improved neuronal viability, reduced oxidative stress and inflammation, and activated Nrf2/HO‐1 signaling.
Rishika Dhapola +4 more
wiley +1 more source
Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health
Ibrain, EarlyView.An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi +4 more
wiley +1 more source
The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse. [PDF]
EMBO J, 2023 Danielli S +11 more
europepmc +1 more source
, 2020 The immunological synapse is a highly structured and molecularly dynamic interface between communicating immune cells. Although the immunological synapse promotes T cell activation by dendritic cells, the specific organization of the immunological ...
Dessislava Malinova (8345460) +9 more
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