Results 131 to 140 of about 241,841 (240)
The micro- and nanoscale architecture of the immunological synapse
, 2010 In this chapter we discuss the importance of micrometer- and nanometer-scale spatial structuring to cellular signaling in the immunological synapse – the contact region between an antigen-presenting cell (APC) and a T cell – focusing on the use of ...
Iain E. Dunlop +5 more
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Interdisciplinary Medicine, EarlyView.This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang +8 more
wiley +1 more source
Molecular Genetic Analysis and Prenatal Diagnosis of a Family With MECP2 Duplication Syndrome
Journal of Clinical Laboratory Analysis, EarlyView.Combined low‐pass CNV‐seq and MLPA identified an inherited Xq28 duplication encompassing MECP2 in a 15‐week male fetus and his affected older brother, transmitted from an asymptomatic mother. This integrated strategy enabled accurate pedigree analysis and prenatal diagnosis of MECP2 duplication syndrome, supporting genetic counseling and reproductive ...
FengQiu Lin +9 more
wiley +1 more source
The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario +3 more
wiley +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Long‐term blood pressure variability (BPV) is associated with cognitive decline, yet the underlying mechanisms have not been fully elucidated. Purpose To investigate the associations between long‐term BPV and hippocampal subfield volume and cognitive function and to assess the mediation effect of hippocampal subfield volume.
Fei Li +17 more
wiley +1 more source
Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair
The Laryngoscope, EarlyView.Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt +10 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans
Topics in Cognitive Science, EarlyView., 2023 Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica +3 more
wiley +1 more source
A life dedicated to pharmacy [PDF]
, 2015 The Synapse meets Mary Ann Sant Fournier presently President of the Malta Chamber of Pharmacists, and visiting Senior Lecturer at the Faculty of Medicine & Surgery, UOM.peer ...
Sant Fournier, Mary Ann, The Synapse
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