Results 161 to 170 of about 226,715 (279)

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Methods of Machine Learning-Based Chimeric Antigen Receptor Immunological Synapse Quality Quantification. [PDF]

open access: yesMethods Mol Biol, 2023
Gan J   +7 more
europepmc   +1 more source

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Distal 1q43q44 deletions lead to a consistent neurodevelopmental phenotype characterized by microcephaly, corpus callosum abnormalities, and developmental delay. Despite differences in genomic architecture, overlapping deletions affecting dosage‐sensitive genes such as AKT3, HNRNPU, and ZBTB18 define the core phenotype.
Ma. Guadalupe Domínguez‐Quezada   +6 more
wiley   +1 more source

Long‐Term Blood Pressure Variability, Hippocampal Subfield Volume and Cognitive Decline: A Population‐Based Prospective MRI Study

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Long‐term blood pressure variability (BPV) is associated with cognitive decline, yet the underlying mechanisms have not been fully elucidated. Purpose To investigate the associations between long‐term BPV and hippocampal subfield volume and cognitive function and to assess the mediation effect of hippocampal subfield volume.
Fei Li   +17 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

open access: yesThe Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen   +3 more
wiley   +1 more source

Immunological synapses in infectious diseases [PDF]

open access: yesBrazilian Journal of Infectious Diseases, 2007
Siqueira-Batista, Rodrigo   +2 more
openaire   +4 more sources

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