Results 11 to 20 of about 142,022 (295)

Blood–Brain Barrier Breakdown: An Emerging Biomarker of Cognitive Impairment in Normal Aging and Dementia

open access: yesFrontiers in Neuroscience, 2021
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized microenvironment of the neural tissue. It separates the peripheral circulatory system from the brain parenchyma while facilitating communication.
Basharat Hussain   +3 more
doaj   +1 more source

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration

open access: yesFrontiers in Immunology, 2017
As potent antigen-presenting cells, dendritic cells (DCs) are essential for the initiation of effective antiviral immune responses. Viruses and especially herpesviruses, which are able to establish lifelong persistence, exploit several immune evasion ...
Christiane S. Heilingloh   +7 more
doaj   +1 more source

Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesAAS Open Research, 2020
Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on ...
Jonathan Nsamba   +9 more
doaj   +1 more source

AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-α

open access: yesFrontiers in Oncology, 2021
TNF-α plays a crucial role in cancer initiation and progression by enhancing cancer cell proliferation, survival, and migration. Even though the known functional role of AWP1 (zinc finger AN1 type-6, ZFAND6) is as a key mediator of TNF-α signaling, its ...
Eun-Young Kim   +24 more
doaj   +1 more source

Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]

open access: yes, 2019
Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk   +5 more
core   +1 more source

Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]

open access: yes, 2020
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P.   +4 more
core   +2 more sources

The Role of Immune Cells in Post-Stroke Angiogenesis and Neuronal Remodeling: The Known and the Unknown

open access: yesFrontiers in Immunology, 2021
Following a cerebral ischemic event, substantial alterations in both cellular and molecular activities occur due to ischemia-induced cerebral pathology.
Yinzhong Ma   +4 more
doaj   +1 more source

Immunomodulation stimulates the innervation of engineered tooth organ [PDF]

open access: yes, 2014
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault   +5 more
core   +5 more sources

Allergen Immunotherapy and Tolerance

open access: yesAllergology International, 2013
Successful allergen-specific immunotherapy (AIT) is associated with a marked decrease in symptoms on allergen exposure, a reduced requirement for 'rescue' anti-allergic drugs and improvement in patients' quality of life.
Tomokazu Matsuoka   +2 more
doaj   +1 more source

Ethical and practical considerations arising from community consultation on implementing controlled human infection studies using Schistosoma mansoni in Uganda

open access: yesGlobal Bioethics, 2022
Issues related to controlled human infection studies using Schistosoma mansoni (CHI-S) were explored to ensure the ethical and voluntary participation of potential CHI-S volunteers in an endemic setting in Uganda.
Moses Egesa   +8 more
doaj   +1 more source

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