Results 21 to 30 of about 142,022 (295)

Dissecting the role of CSF2RB expression in human regulatory T cells

Frontiers in Immunology, 2022
Colony stimulating factor 2 receptor subunit beta (CSF2RB; CD131) is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. Interestingly, FOXP3+ regulatory T cells (
Beatriz F. Côrte-Real, Beatriz F. Côrte-Real, Rebeca Arroyo Hornero, Rebeca Arroyo Hornero, Aleksandra Dyczko, Aleksandra Dyczko, Ibrahim Hamad, Ibrahim Hamad, Markus Kleinewietfeld, Markus Kleinewietfeld, Markus Kleinewietfeld   +10 more
doaj   +1 more source

Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]

, 2016
Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai, Liu, Yan-Qun, Xie, Chong, Zhang, Guang-Xian   +3 more
core   +2 more sources

Unsupervised title and abstract screening for systematic review: a retrospective case-study using topic modelling methodology

Systematic Reviews, 2023
Background The importance of systematic reviews in collating and summarising available research output on a particular topic cannot be over-emphasized.
Agnes Natukunda, Leacky K. Muchene
doaj   +1 more source

Anti-COVID-19 drug candidates: A review on potential biological activities of natural products in the management of new coronavirus infection

Journal of Traditional and Complementary Medicine, 2021
Background and aim: The novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now become a worldwide pandemic bringing over 71 million confirmed cases, while the specific drugs and vaccines ...
Anchalee Prasansuklab, Atsadang Theerasri, Panthakarn Rangsinth, Chanin Sillapachaiyaporn, Siriporn Chuchawankul, Tewin Tencomnao   +5 more
doaj   +1 more source

Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort [version 1; peer review: 1 approved, 2 approved with reservations]

AAS Open Research, 2019
Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on ...
Jonathan Nsamba, Swaib A. Lule, Benigna Namara, Christopher Zziwa, Hellen Akurut, Lawrence Lubyayi, Florence Akello, Josephine Tumusiime, Alison M. Elliott, Emily L. Webb   +9 more
doaj   +1 more source

Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda

Frontiers in Immunology, 2020
Background: BCG has low efficacy in tropical countries. We hypothesized that maternal latent Mycobacterium tuberculosis (M.tb) infection (LTBI) results in fetal tolerance to mycobacterial antigens and impaired responses to BCG immunization.Methods: We ...
Lawrence Lubyayi, Lawrence Lubyayi, Patrice A. Mawa, Patrice A. Mawa, Grace Nabakooza, Marjorie Nakibuule, John Vianney Tushabe, Joel Serubanja, Dorothy Aibo, Hellen Akurut, Josephine Tumusiime, Mateusz Hasso-Agopsowicz, Pontiano Kaleebu, Pontiano Kaleebu, Jonathan Levin, Hazel M. Dockrell, Steven Smith, Emily L. Webb, Alison M. Elliott, Alison M. Elliott, Stephen Cose, Stephen Cose   +21 more
doaj   +1 more source

Contrasting impact of rural, versus urban, living on glucose metabolism and blood pressure in Uganda [version 2; peer review: 2 approved]

Wellcome Open Research, 2020
Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation.
Richard E. Sanya, Irene Andia Biraro, Margaret Nampijja, Christopher Zziwa, Carol Nanyunja, Denis Nsubuga, Samuel Kiwanuka, Josephine Tumusiime, Jacent Nassuuna, Bridgious Walusimbi, Stephen Cose, Ponsiano Ocama, Richard K. Grencis, Alison M. Elliott, Emily L. Webb   +14 more
doaj   +1 more source

Mesenchymal stem cells for management of rheumatoid arthritis : immune modulation, repair or both? [PDF]

, 2018
The authors are grateful for support to their research from Arthritis Research UK (grants 19271, 19429, 19667, 20050, 20775) and the Medical Research Council (grant no.
Ansboro, Sharon, de Bari, Cosimo, Roelofs, Anke J.   +2 more
core   +1 more source

Assessment of the immunomodulatory properties of the probiotic strain Lactobacillus paracasei K5 in vitro and in vivo [PDF]

, 2020
Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain that has been isolated from dairy products. Previous studies have established its probiotic potential in a series of in vitro tests, including molecular characterization, safety profiling,
Alexopoulos, Athanasios, Bezirtzoglou, Eugenia, Botaitis, Sotiris, Chondrou, Pelagia, Galanis, Alex, Karapetsas, Athanasios, Kiousi, Despoina Eugenia, Plessas, Stavros, Vasileiadis, Stavros, Ypsilantis, Petros   +9 more
core   +2 more sources

Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells

Frontiers in Immunology, 2021
FOXP3+ regulatory T cells (Tregs) are central for maintaining peripheral tolerance and immune homeostasis. Because of their immunosuppressive characteristics, Tregs are a potential therapeutic target in various diseases such as autoimmunity ...
Lauren Van Zeebroeck, Lauren Van Zeebroeck, Rebeca Arroyo Hornero, Rebeca Arroyo Hornero, Beatriz F. Côrte-Real, Beatriz F. Côrte-Real, Ibrahim Hamad, Ibrahim Hamad, Torsten B. Meissner, Markus Kleinewietfeld, Markus Kleinewietfeld   +10 more
doaj   +1 more source