Results 31 to 40 of about 142,022 (295)
Cyclic β-glucans at the bacteria–host cells interphase: One sugar ring to rule them all [PDF]
, 2018 Cyclic β‐1,2‐D‐glucans (CβG) are natural bionanopolymers present in the periplasmic space of many Proteobacteria. These molecules are sugar rings made of 17 to 25 D‐glucose units linked exclusively by β‐1,2‐glycosidic bonds.
Arce Gorvel, Vilma +4 more
core +1 more source
Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy
EMBO Molecular Medicine, 2019 The majority of lung cancer patients progressing from conventional therapies are refractory to PD‐L1/PD‐1 blockade monotherapy. Here, we show that baseline systemic CD4 immunity is a differential factor for clinical responses.
Miren Zuazo +14 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Polydopamine (PDA) is a biocompatible cell-adhesive polymer with versatile applications in biomedical devices. Previous studies have shown that PDA coating could improve cell adhesion and differentiation of human mesenchymal stem cells (hMSCs).
Javad Harati +14 more
doaj +1 more source
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core +2 more sources
Targeting the tumor microenvironment in colorectal peritoneal metastases
, 2020 Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim +4 more
core +1 more source
Current Animal Models of Postoperative Spine Infection and Potential Future Advances. [PDF]
, 2015 Implant related infection following spine surgery is a devastating complication for patients and can potentially lead to significant neurological compromise, disability, morbidity, and even mortality.
Bernthal, NM +7 more
core +1 more source
Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion
Molecules, 2021 Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas +6 more
doaj +1 more source
Cell Therapy for Type 1 Diabetes [PDF]
, 2014 Acknowledgements The work described in this review was supported by a grant from the MRC. K.R.M. is supported by a fellowship from the Scottish Translational Medicines and Therapeutics Initiative through the Wellcome Trust.Peer reviewedPublisher ...
Docherty, H. M. +3 more
core +1 more source
European Journal of Inflammation, 2014 Probiotic bacteria have been shown to have health benefits in various situations (inflammation, allergy, infection). We previously showed that a bacteria-free fermentation product of Bifidobacterium breve C50 (BbC50sn) induced high IL-10 secretion by ...
L. Martin +9 more
doaj +1 more source
Effects of Methotrexate on IL-6alphar, VCAM-1 and NF Kappa B Expression in a Rat Model of Metabolic Syndrome [PDF]
, 2016 Background: In this study, we used Methotrexate (Mtx) to examine the role of immunomodulation on the activation of IL-6 and VCAM-1, which could generate a microenvironment that supports cardiovascular remodelling.Methods: Male WKY and SHR rats were ...
Diez, Emiliano Raúl +4 more
core +1 more source