Results 31 to 40 of about 74,853 (208)
Interactions between species introduce spurious associations in microbiome studies [PDF]
2018. PLoS Comput Biol 14(1): e1005939, 2017 Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, however, reflect not only direct associations with the phenotype, but also indirect effects due to ...
arxiv +1 more source
Wellcome Open Research, 2020 Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation.
Richard E. Sanya +14 more
doaj +1 more source
Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells
Frontiers in Immunology, 2021 FOXP3+ regulatory T cells (Tregs) are central for maintaining peripheral tolerance and immune homeostasis. Because of their immunosuppressive characteristics, Tregs are a potential therapeutic target in various diseases such as autoimmunity ...
Lauren Van Zeebroeck +10 more
doaj +1 more source
Measles and immunomodulation [PDF]
Journal of Allergy and Clinical Immunology, 2008 n ...
openaire +3 more sources
Ectosomes as immunomodulators [PDF]
Seminars in Immunopathology, 2010 Considerable progress has been made in recognizing microvesicles as important mediators of intercellular communication rather than irrelevant cell debris. Microvesicles released by budding directly from the cell membrane surface (i.e., ectocytosis) either spontaneously or in response to various stimuli are called shed vesicles or ectosomes.
Sadallah, Salima +2 more
openaire +4 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Polydopamine (PDA) is a biocompatible cell-adhesive polymer with versatile applications in biomedical devices. Previous studies have shown that PDA coating could improve cell adhesion and differentiation of human mesenchymal stem cells (hMSCs).
Javad Harati +14 more
doaj +1 more source
A Nested Multi-Scale Model for COVID-19 Viral Infection [PDF]
arXiv, 2021 In this study, we develop and analyze a nested multi-scale model for COVID -19 disease that integrates within-host scale and between-host scale sub-models. First, the well-posedness of the multi-scale model is discussed, followed by the stability analysis of the equilibrium points.
arxiv
Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy
EMBO Molecular Medicine, 2019 The majority of lung cancer patients progressing from conventional therapies are refractory to PD‐L1/PD‐1 blockade monotherapy. Here, we show that baseline systemic CD4 immunity is a differential factor for clinical responses.
Miren Zuazo +14 more
doaj +1 more source
Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion
Molecules, 2021 Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas +6 more
doaj +1 more source
Immunomodulation of immunothrombocytopenia [PDF]
Seminars in Hematology, 2016 Current treatment strategies in patients with immunothrombocytopenia (ITP) include immunosuppression and the stimulation of platelet production. Research over the last decade has emphasized the important role of Fc-receptors as key molecules responsible for autoantibody-mediated platelet depletion, allowing for a more specific targeting of this pathway
openaire +3 more sources