Results 111 to 120 of about 2,997 (217)
EJNMMI Radiopharmacy and ChemistryBackground Triple-negative breast cancer (TNBC) is one of the most lethal malignant tumors among women, characterized by high invasiveness, high heterogeneity, and lack of specific therapeutic targets such as estrogen receptor, progesterone receptor, and
Yitian Wu +5 more
doaj +1 more source
A pretargeting system for tumor PET imaging and radioimmunotherapy
Frontiers in Pharmacology, 2015 Labeled antibodies, as well as their fragments and antibody-derived recombinant constructs, have long been proposed as general vectors to target radionuclides to tumor lesions for imaging and therapy.
Françoise eKraeber-Bodéré +10 more
doaj +1 more source
Nectin4‐targeted molecular imaging in solid tumors: Current status and future perspectives
VIEW, Volume 6, Issue 3, June 2025.In this review, we provide a concise overview of the mechanisms by which Nectin4 contributes to the pathogenesis of various malignancies and detail the classes of Nectin4‐targeted molecular probes. We then delve into the significant advancements in Nectin4‐targeted molecular imaging techniques, encompassing both nuclear medicine and optical imaging ...
Yongshun Liu +6 more
wiley +1 more source
Recent Updates of PET in Lymphoma: FDG and Beyond
BiomedicinesLymphoma is one of the most common cancers worldwide, categorized into Hodgkin lymphoma and non-Hodgkin lymphoma. 18F-fluorodeoxyglucose positron emission tomography (FDG PET) has become an essential imaging tool for evaluating patients with lymphoma in ...
Sung-Yong Kim +4 more
doaj +1 more source
Journal of Computational Chemistry, Volume 46, Issue 14, May 30, 2025.Zirconium is of significant interest in the domain of material science and biomedical applications. The development of fast and accurate computational methodologies is of paramount importance for studying the properties of these materials. This article presents an extension of the well‐established DFTB3/3OB approach to Zr, with the objective of ...
Armin Penz +4 more
wiley +1 more source
Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells [PDF]
, 2018 Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival.
Anushka Dongre +55 more
core +1 more source
Isopeptidic Desferrioxamine Analogues: The Role of Hydroxamate Spacing for Chelation of Zr4+
ChemMedChem, Volume 20, Issue 6, March 15, 2025.Isopeptidic analogues of the natural product desferrioxamine have been synthesized by solid phase peptide synthesis. Denticity and spacing of hydroxamic acids influence the stability of corresponding Zr complexes and octadentate chelators with a “native” nine carbon spacer form the most stable Zr‐complexes.
Lasse Outzen +4 more
wiley +1 more source
OncoImmunology, 2017 Radiation therapy (RT) can induce upregulation of programmed death ligand 1 (PD-L1) on tumor cells or myeloid cells, which may affect response to PD-1-based immunotherapy.
Masahiro Kikuchi +8 more
doaj +1 more source
Molecular Imaging of Invasive Pulmonary Aspergillosis using ImmunoPET/MRI: The Future Looks Bright [PDF]
, 2018 This is the final version of the article. Available from Frontiers Media via the DOI in this record.Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of immuno-compromised humans caused by the ubiquitous environmental mould ...
Thornton, CR
core +1 more source
Nature CommunicationsThe COVID-19 pandemic has caused at least 780 million cases globally. While available treatments and vaccines have reduced the mortality rate, spread and evolution of the virus are ongoing processes.
Alexandra Detrille +15 more
semanticscholar +1 more source