Precision immunity: Immunoscore and neoadjuvant treatment in bladder cancer [PDF]
OncoImmunology, 2021 This review details the clinical utility of Immunoscore, measuring the immune response to cancer within the tumor microenvironment, in bladder cancer. Immunoscore was recently introduced into ESMO Clinical Practice Guidelines for gastrointestinal cancer ...
Jérôme Galon +2 more
exaly +4 more sources
Usefulness and robustness of Immunoscore for personalized management of cancer patients [PDF]
OncoImmunology, 2020 This review details the analytical performance characteristics of the consensus Immunoscore, measuring the immune response to cancer, improving the estimation of risk of recurrence, and predicting response to treatment for patients with colon cancer. The
Jérôme Galon +2 more
exaly +4 more sources
The prognostic value of immunoscore in the early-onset colorectal cancer [PDF]
BMC GastroenterologyBackground The purpose of this study was to explore the prognostic value of Immunoscore in patients with early-onset colorectal cancer. Methods We retrospectively analyzed 708 colorectal adenocarcinoma patients (2017–2020), ultimately including 36 early ...
Xinchun Wu +3 more
doaj +4 more sources
Light on life: immunoscore immune-checkpoint, a predictor of immunotherapy response
OncoImmunology, 2023 In the last decade, a plethora of immunotherapeutic strategies have been designed to modulate the tumor immune microenvironment. In particular, immune checkpoint (IC) blockade therapies present the most promising advances made in cancer treatment in ...
Carlotta Antoniotti +2 more
exaly +3 more sources
The prognostic value of Immunoscore in patients with cancer: A pooled analysis of 10,328 patients
International Journal of Biological Markers, 2020 Objectives: Over the past decade, some publications have reported that Immunoscore was associated with the prognosis of several cancers. To better understand this issue, we conducted this pooled analysis.
Xingxia Zhang, Yong Zhou, Ka Li
exaly +2 more sources
International Journal of Biological Markers, 2020 Purpose: Immunoscore was established to evaluate the prognosis of cancer patients. However, the feasibility of Immunoscore for the prognosis of cervical cancer remains unknown. To find other prognostic markers that contribute to immunological importance,
Ge Lou, Tongsen Zheng
exaly +2 more sources
Immunoscore Predicts Survival in Early-Stage Lung Adenocarcinoma Patients
Frontiers in Oncology, 2020 Background: The lung cancer staging system is insufficient for a comprehensive evaluation of patient prognosis. We constructed a novel immunoscore model to predict patients with high risk and poor survival.Method: Immunoscore was developed based on z ...
Zihuan Zhao
exaly +3 more sources
Clinical and immunopathological evaluation and its comparison with IHC consensus molecular subtypes of colorectal cancer [PDF]
Scientific ReportsThis study examined the prognostic significance of immunoscore within consensus molecular subtypes (CMS), tumour budding (TB), and macrophage infiltration in colorectal cancer (CRC). A retrospective series was analysed using immunohistochemical staining,
Eduardo Feliciangeli +15 more
doaj +2 more sources
A nomogram based on collagen signature for predicting the immunoscore in colorectal cancer
Frontiers in Immunology, 2023 ObjectivesThe Immunoscore can categorize patients into high- and low-risk groups for prognostication in colorectal cancer (CRC). Collagen plays an important role in immunomodulatory functions in the tumor microenvironment (TME).
Shuangmu Zhuo +2 more
exaly +3 more sources
Combining immunoscore and tumor budding in colon cancer: an insightful prognostication based on the tumor-host interface [PDF]
Journal of Translational MedicineBackground Tumor Budding (TB) and Immunoscore are independent prognostic markers in colon cancer (CC). Given their respective representation of tumor aggressiveness and immune response, we examined their combination in association with patient disease ...
T. S. Haddad +11 more
doaj +2 more sources