Results 91 to 100 of about 29,033 (245)

Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice [PDF]

open access: yes, 2013
Incontinence and sexual dysfunction are often increased in the aged human population. In rats and mice the pattern of micturition and faecal clearance also changes with ageing and is suggestive of bladder and bowel ...
Black, G.   +4 more
core  

Accelerated epigenetic aging in Werner syndrome. [PDF]

open access: yes, 2017
Individuals suffering from Werner syndrome (WS) exhibit many clinical signs of accelerated aging. While the underlying constitutional mutation leads to accelerated rates of DNA damage, it is not yet known whether WS is also associated with an increased ...
Flunkert, Julia   +5 more
core   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

open access: yesActa Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Cosmetic Adverse Reactions and Prognostic Factors: A Retrospective Cohort Study in Wuhan, China

open access: yesContact Dermatitis, EarlyView.
This study reveals that being under 20 or having a history of allergies significantly increases the risk of long‐term symptoms after a cosmetic adverse reaction. These findings help dermatologists identify high‐risk patients for proactive management and tailored preventive strategies.
Ayan Hasen   +4 more
wiley   +1 more source

CMV and Immunosenescence: from basics to clinics

open access: yesImmunity & Ageing, 2012
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people.
Solana Rafael   +36 more
doaj   +1 more source

The systemic environment: at the interface of aging and adult neurogenesis. [PDF]

open access: yes, 2017
Aging results in impaired neurogenesis in the two neurogenic niches of the adult mammalian brain, the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricle.
Smith, Lucas K   +2 more
core   +1 more source

Ethical and Regulatory Considerations in the Clinical Translation of Pluripotent Stem Cell‐Derived NK Cell Therapies

open access: yesCell Proliferation, EarlyView.
Advancements in the generation of human pluripotent stem cell‐derived natural killer (PSC‐NK) cells have attracted considerable attention within the biomedical research community, offering a promising off‐the‐shelf technique for universal immune therapy.
Qianwen Chen   +5 more
wiley   +1 more source

Inflammation, genetic background and longevity [PDF]

open access: yes, 2010
Ageing is an inexorable intrinsic process that affects all cells, tissues, organs and individuals. Due to a diminished homeostasis and increased organism frailty, ageing causes a reduction of the response to environmental stimuli and, in general, is
A Panda   +65 more
core   +1 more source

New Hydrophilic Helixone Dialyzers as an Alternative for Hemodialysis Patients With Membrane Hypersensitivity Reactions: A Retrospective Single‐Cohort Study

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Synthetic dialysis membranes, particularly those composed of polysulfone blended with polyvinylpyrrolidone, are commonly used in hemodialysis due to their efficiency. However, hypersensitivity reactions—often atypical and not fitting traditional type A and B classifications—have increasingly been reported.
Víctor Joaquín Escudero‐Saiz   +9 more
wiley   +1 more source

The role of inflammation in age-related disease. [PDF]

open access: yes, 2013
The National Institutes of Health (NIH) Geroscience Interest Group (GSIG) sponsored workshop, The Role of Inflammation inAge-Related Disease, was held September 6th-7th, 2012 in Bethesda, MD.
Augustine, Alison Deckhut   +9 more
core   +2 more sources

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