Results 81 to 90 of about 29,526 (256)
Age-related impairment of human T lymphocytes' activation: specific differences between CD4+ and CD8+ subsets [PDF]
, 2006 The relevance of physiological immune aging is of great interest with respect to determining disorders with pathologic immune function in aging individuals.
Eckert, Anne +4 more
core
B Cells Compartment in Centenarian Offspring and Old People [PDF]
, 2010 Immunosenescence is considered a major contributory factor to the increased frequency of morbidity and mortality among elderly. On the other hand centenarians are considered the best example of successful ageing.
BUFFA, Silvio +7 more
core +1 more source
Immunosenescence in neurocritical care [PDF]
Journal of Intensive Care, 2018 Several advanced and developing countries are now entering a superaged society, in which the percentage of elderly people exceeds 20% of the total population. In such an aging society, the number of age-related diseases such as malignant tumors, diabetes, and severe infections including sepsis is increasing, and patients with such disorders often find ...
Inoue, Shigeaki +2 more
openaire +3 more sources
Mapping the subgingival HerBiome and HisBiome over the human healthspan
Journal of Periodontology, EarlyView.Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam +3 more
wiley +1 more source
Immunosenescence and Vaccination [PDF]
Immunity & Ageing, 2005 Abstract The problems associated with the ageing immune system and vaccination were discussed recently at an international workshop at the Jenner Institute for Vaccine Research, Compton, UK, 6–7 October, 2005. This is a commentary on that session.
openaire +3 more sources
Frontiers in Immunology, 2016 The goal of annual influenza vaccination is to reduce mortality and morbidity associated with this disease through the generation of protective immune responses.
Richard Kennedy +6 more
doaj +1 more source
Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]
, 2013 Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances +5 more
core
Immunosenescence of Polymorphonuclear Neutrophils [PDF]
The Scientific World JOURNAL, 2010 All immune cells are affected by aging, contributing to the high susceptibility to infections and increased mortality observed in the elderly. The effect of aging on cells of the adaptive immune system is well documented. In contrast, knowledge concerning age-related defects of polymorphonuclear neutrophils (PMN) is limited.
Inga Wessels +3 more
openaire +3 more sources
Dasatinib and quercetin prevent alveolar bone loss in aged mice
Journal of Periodontology, EarlyView.Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli +7 more
wiley +1 more source
Alcohol consumption and leukocyte telomere length. [PDF]
, 2019 The relationship between alcohol consumption and mortality generally exhibits a U-shaped curve. The longevity observed with moderate alcohol consumption may be explained by other confounding factors, and, if such a relationship is present, the mechanism ...
Dixit, Shalini +9 more
core +2 more sources