Results 81 to 90 of about 20,223 (261)

Shortened outreach periodontal therapy in nursing home residents with periodontitis: A randomized controlled trial

Journal of Periodontology, EarlyView.
Abstract Background We examined the clinical effectiveness of shortened outreach periodontal therapy for 3 months in nursing home residents with periodontitis versus controls (no therapy). Methods Nursing home residents with periodontitis were randomly assigned to either (a) one‐time, shortened outreach periodontal therapy adapted to German statutory ...
Anna G. Barbe, Dalia Beck, Martin Hellmich, Max von Kohout, Sonja H. M. Derman, Dirk Bleiel   +5 more
wiley   +1 more source

Data_Sheet_1_Radiation therapy induces immunosenescence mediated by p90RSK.pdf

, 2022
Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches.
Venkata S. K. Samanthapudi (13286529), Roza Nurieva (46641), Syed Wamique Yusuf (6822308), Anita Deswal (7923626), Ling-Ling Lee (13286532), Haizi Cheng (6002156), Nicolas L. Palaskas (9637787), Steven H. Lin (7045541), John P. Cooke (259814), Keri L. Schadler (9637793), El-ad David Amir (6819107), Masaki Imanishi (515835), Sai-Ching J. Yeung (9270842), Eduardo Chini (14074563), Momoko Yoshimoto (288647), Joerg Herrmann (333656), Xiaolei Xu (81386), Cielito Reyes-Gibby (3174045), Sivareddy Kotla (5064794), Kyung Ae Ko (5064797), Nhat-Tu Le (5723063), Jun-ichi Abe (725829), Zhongxing Liao (220056), Jared K. Burks (13907542), Michihiro Kobayashi (10718499)   +24 more
core   +1 more source

Immune-Inflammatory Response in Lifespan—What Role Does It Play in Extreme Longevity? A Sicilian Semi- and Supercentenarians Study

Biology
Studying models of healthy aging and exceptional longevity is crucial to understanding a possible longevity signature, as most show resistance to age-related diseases.
Giulia Accardi, Anna Calabrò, Rosalia Caldarella, Calogero Caruso, Marcello Ciaccio, Marta Di Simone, Mattia Emanuela Ligotti, Serena Meraviglia, Rosa Zarcone, Giuseppina Candore, Anna Aiello   +10 more
doaj   +1 more source

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos, Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Alba Sánchez‐Barco, Iryna Kuz, Marta Relvas, Susana Belén Bravo, Carlos Balsa‐Castro, Inmaculada Tomás   +8 more
wiley   +1 more source

Cellular Senescence, Immunosenescence and HIV

, 2016
Aging is a complex biological process that leads to several physiological changes. Among these changes, the most striking are those involving the innate and adaptive parts of the immune system.
Dupuis G., Pawelec G., Cossarizza A., Herbein G., Frost E., Fulop T., Larbi A., Witkowski J. M.   +7 more
core   +1 more source

Radiation therapy induces immunosenescence mediated by p90RSK

, 2022
Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches.
Le, Nhat-Tu, Yeung, Sai-Ching J., Samanthapudi, Venkata S. K., Burks, Jared K., Palaskas, Nicolas L., Lin, Steven H., Lee, Ling-Ling, Burks, Jared K, Liao, Zhongxing, Cooke, John P., Schadler, Keri L, Cheng, Haizi, Deswal, Anita, Abe, Jun-ichi, Samanthapudi, Venkata S K, Yeung, Sai-Ching J, Herrmann, Joerg, Ko, Kyung Ae, Palaskas, Nicolas L, Yusuf, Syed Wamique, Yoshimoto, Momoko, Xu, Xiaolei, Nurieva, Roza, Kotla, Sivareddy, Cooke, John P, Imanishi, Masaki, Reyes-Gibby, Cielito, Lin, Steven H, Schadler, Keri L., Amir, El-ad David, Kobayashi, Michihiro, Chini, Eduardo   +31 more
core   +1 more source

Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination

Frontiers in Immunology, 2016
The goal of annual influenza vaccination is to reduce mortality and morbidity associated with this disease through the generation of protective immune responses.
Richard Kennedy, Inna Ovsyannikova, Iana Haralambieva, Ann Oberg, Michael T Zimmermann, Diane Grill, Gregory A. Poland   +6 more
doaj   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

Journal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit, Marilena Vered, Michael Saminsky, Liat Chaushu   +3 more
wiley   +1 more source

Innate immunosenescence and sepsis in the elderly: mechanisms and innate immune modulation strategies

This study aimed to investigate the mechanisms of innate immunosenescence in elderly patients with sepsis and to evaluate the potential application of innate immune modulation strategies in clinical management.
Kai Sheng, Jing Cheng, Donghua Cao, Danfeng Zhang   +3 more
core   +1 more source

Mapping the subgingival HerBiome and HisBiome over the human healthspan

Journal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam, Kazune Pax, Michelle Lee‐Scott Beverly, Purnima S. Kumar   +3 more
wiley   +1 more source