Results 71 to 80 of about 5,611 (223)
BiologyStudying models of healthy aging and exceptional longevity is crucial to understanding a possible longevity signature, as most show resistance to age-related diseases.
Giulia Accardi +10 more
doaj +1 more source
Update of Immunosenescence in Cerebral Small Vessel Disease
Frontiers in Immunology, 2020 Aging of the central nervous system (CNS) is closely associated with chronic sterile low-grade inflammation in older organisms and related immune response.
Banghao Jian +5 more
doaj +1 more source
Zinc, metallothioneins and immunosenescence [PDF]
Proceedings of the Nutrition Society, 2010 Ageing is an inevitable biological process with gradual and spontaneous biochemical and physiological changes and increased susceptibility to diseases. The nutritional factor, zinc, may remodel these changes with subsequent healthy ageing, because zinc improves the inflammatory/immune response as shown byin vitroandin vivostudies.
Mocchegiani, E. +9 more
openaire +2 more sources
Cellular Senescence, Immunosenescence and HIV
, 2016 Aging is a complex biological process that leads to several physiological changes. Among these changes, the most striking are those involving the innate and adaptive parts of the immune system.
Dupuis G. +7 more
core +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Routine TBNK immunophenotyping detects the major lymphocyte compartments but may underestimate the biologically relevant variation contributed by less frequent but well‐defined minor lymphocyte subsets. This study evaluated whether extending routine TBNK immunophenotyping with minor lymphocyte subsets provides complementary, analytically ...
Carlos Agustin Villegas Valverde +5 more
wiley +1 more source
Emergence of T cell immunosenescence in diabetic chronic kidney disease
Immunity & Ageing, 2020 Background Type 2 diabetes is an important challenge given the worldwide epidemic and is the most important cause of end-stage renal disease (ESRD) in developed countries.
Yen-Ling Chiu +10 more
doaj +1 more source
This study aimed to investigate the mechanisms of innate immunosenescence in elderly patients with sepsis and to evaluate the potential application of innate immune modulation strategies in clinical management.
Kai Sheng +3 more
core +1 more source
The Role of Immunosenescence in Neurodegenerative Diseases [PDF]
, 2018 Aging is characterized by the progressive decline of physiological function and tissue homeostasis leading to increased vulnerability, degeneration, and death.
Marcella Reale +2 more
core +1 more source
Cheek tooth extraction in geriatric versus non‐geriatric horses
Equine Veterinary Journal, EarlyView.Abstract Background Age‐related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population.
Elias Mair +4 more
wiley +1 more source
Journal of Ageing and LongevityThis study aims to characterise the B cell compartment in a cohort of Sicilian centenarians by analysing absolute CD3−CD19+ lymphocyte counts, in association with age, sex, cytomegalovirus (CMV) serostatus, related to immune ageing, and interleukin (IL ...
Giorgio Bertolazzi +8 more
doaj +1 more source