Results 51 to 60 of about 29,526 (256)
Advanced Materials Technologies, EarlyView.ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani +9 more
wiley +1 more source
AGING MEDICINE, EarlyView.Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu +4 more
wiley +1 more source
Experimental Gerontology, 2023 Senescent cells were recently shown to play a role in aging-related malfunctions and pathologies. This consensus has been facilitated by evidence from senolytic model mice capable of eliminating senescent cells in tissues using well-characterized ...
Yuma Sugiyama +6 more
doaj +1 more source
Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection [PDF]
, 2018 Throughout the lifespan of an individual, the immune system undergoes complex changes while facing novel and chronic infections. Helminths, which infect over one billion people and impose heavy livestock productivity losses, typically cause chronic ...
Babayan, Simon A. +3 more
core +1 more source
Cytometric analysis of immunosenescence [PDF]
Cytometry, 1997 We have been studying the immune system of healthy centenarians for many years, and they provide the best example of successful aging. They are people who have escaped major age-related diseases and reached the extreme limit of human life in good clinical condition.
A. Cossarizza +3 more
openaire +4 more sources
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi +9 more
wiley +1 more source
, 2011 INTRODUCTION: Aging involves various complex cellular and molecular changes, including a general decline in immunological functions known as immunosenescence. The clinical consequences of immunosenescence include increased susceptibility to respiratory infections, neoplasias and cardiovascular diseases.
Torres,Karen Cecília de Lima +6 more
openaire +3 more sources
, 2007 Age-related immunological and endocrinological changes may have implications for resilience to stress in older adults. We hypothesise that the combination of adrenopause and immunesenescence may leave this population particularly vulnerable to the ...
Bauer +21 more
core +1 more source
BMEMat, EarlyView.This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan +15 more
wiley +1 more source
Immunity & AgeingAging is frequently characterized by an inadequate primary vaccine response, likely due to immunosenescence and inflamm-aging, a low-level, chronic inflammatory state.
Anna Aiello +10 more
doaj +1 more source