Results 31 to 40 of about 20,223 (261)
Immunosenescence and multiple sclerosis
, 2022 Changes in the immune system associated with ageing are known as immunosenescence. This is characterised by a decline in immune response, chronic inflammation and an increased risk of autoimmune diseases.
Nowak-Kiczmer, Maria; Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland +3 more
core +1 more source
The impact of senescence-associated T cells on immunosenescence and age-related disorders
Inflammation and Regeneration, 2018 Immunosenescence is age-associated changes in the immunological functions, including diminished acquired immunity against infection, pro-inflammatory traits, and increased risk of autoimmunity.
Yuji Fukushima +2 more
doaj +1 more source
Immunosenescence: molecular mechanisms and diseases
Signal Transduction and Targeted Therapy, 2023 Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms are linked to innate and adaptive immune dysfunction that accompanies aging (known as immunosenescence).
Zaoqu Liu +9 more
doaj +1 more source
Immunosenescence and Vaccination [PDF]
Immunity & Ageing, 2005 Abstract The problems associated with the ageing immune system and vaccination were discussed recently at an international workshop at the Jenner Institute for Vaccine Research, Compton, UK, 6–7 October, 2005. This is a commentary on that session.
openaire +3 more sources
AGE, 2005 Immunosenescence, the aging of the immune system, is well studied in humans. Mammalian immune systems become less capable of fighting pathogens and individuals become more susceptible to infection and cancer in their elder years. Little is currently published on avian immunosenescence even though avian immune function has been well characterized and ...
openaire +2 more sources
Imaging Immunosenescence [PDF]
, 2015 To demonstrate effects of aging visually requires a robust technique that can reproducibly detect small differences in efficiency or kinetics between groups. Investigators of aging will greatly appreciate the benefits of Amnis ImageStream technology ( www.amnis.com/), which combines quantitative flow cytometry with simultaneous high-resolution digital ...
Feng, Qian, Ruth R, Montgomery
openaire +2 more sources
The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases
Mediators of Inflammation, 2010 Obesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune ...
Carmela Rita Balistreri +2 more
doaj +1 more source
Aging-associated immune system changes in multiple myeloma: The dark side of the moon.
Cancer Treatment and Research Communications, 2021 Multiple myeloma (MM) is a disease of the elderly. Changes that occur in the immune system with aging, also known as immunosenescence, have been associated with decreased tumor immunosurveillance and are thought to contribute to the development of MM and
Alissa Visram, Taxiarchis V. Kourelis
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Frontiers in Immunology, 2019 Aging is accompanied by remodeling of the immune system. With time, this leads to a decline in immune efficacy, resulting in increased vulnerability to infectious diseases, diminished responses to vaccination, and a susceptibility to age-related ...
Anna Aiello +9 more
doaj +1 more source