Results 11 to 20 of about 5,611 (223)

Immunosenescence: A Critical Factor Associated With Organ Injury After Sepsis [PDF]

open access: yesFrontiers in Immunology, 2022
Progressive immune dysfunction associated with aging is known as immunosenescence. The age-related deterioration of immune function is accompanied by chronic inflammation and microenvironment changes.
Xuan Lu   +5 more
doaj   +2 more sources

Targeting immunosenescence for improved tumor immunotherapy

open access: yesMedComm
Tumor immunotherapy has significantly transformed the field of oncology over the past decade. An optimal tumor immunotherapy would ideally elicit robust innate and adaptive immune responses within tumor immune microenvironment (TIME).
Zaoqu Liu   +16 more
doaj   +2 more sources

CMV and Immunosenescence: from basics to clinics [PDF]

open access: yesImmunity & Ageing, 2012
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people.
Solana Rafael   +36 more
doaj   +6 more sources

Aging and immunosenescence in invertebrates [PDF]

open access: yesInvertebrate Survival Journal, 2012
Most contemporary research into aging is driven by interest in the human aging process and in interventions that attenuate the normal and pathophysiological effects of aging, or senescence.
D Stanley
doaj   +3 more sources

Immunosenescence

open access: yes, 2011
INTRODUCTION: Aging involves various complex cellular and molecular changes, including a general decline in immunological functions known as immunosenescence. The clinical consequences of immunosenescence include increased susceptibility to respiratory infections, neoplasias and cardiovascular diseases.
Torres,Karen Cecília de Lima   +6 more
core   +4 more sources

Global research trends of immunosenescence and immunotherapy: A bibliometric study

open access: yesHuman Vaccines & Immunotherapeutics
Immunosenescence refers to the gradual decline in immune system function with age, increasing susceptibility to infections and cancer in the elderly. The advent of novel immunotherapies has revolutionized the field of cancer treatment.
Wendi Li, Lin Xiao, Haiyang Li, Wei Cui
doaj   +2 more sources

Immunosenescence and multiple sclerosis [PDF]

open access: yes, 2022
Changes in the immune system associated with ageing are known as immunosenescence. This is characterised by a decline in immune response, chronic inflammation and an increased risk of autoimmune diseases.
Nowak-Kiczmer, Maria; Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland   +3 more
core   +1 more source

Elucidation of the role of nucleolin as a cell surface receptor for nucleic acid-based adjuvants

open access: yesnpj Vaccines, 2022
Nucleic acid-based adjuvants such as CpG oligonucleotides (CpG ODNs) and poly(I:C) are potential vaccine adjuvants for infectious diseases and cancers. However, the mechanism by which their cell surface receptors promote their uptake into dendritic cells
Satoki Kitagawa   +5 more
doaj   +1 more source

Report from the second cytomegalovirus and immunosenescence workshop. [PDF]

open access: yes, 2011
The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory frequency, inflation and immunosenescence;
Pawelec, Graham   +328 more
core   +3 more sources

Autoimmune diseases are more common in women: insights into sex and gender differences in autoimmunity [PDF]

open access: yesExploration of Immunology
Autoimmune diseases (ADs) comprise a heterogeneous group of disorders characterised by a breakdown of immune tolerance and chronic immune-mediated tissue damage.
Anna Calabrò   +4 more
doaj   +1 more source

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