Results 21 to 30 of about 5,611 (223)

Immunosenescence and Cytomegalovirus: where do we stand after a decade? [PDF]

open access: yes, 2010
Since Looney at al. published their seminal paper a decade ago it has become clear that many of the differences in T cell immunological parameters observed between young and old people are related to the age-associated increasing prevalence of infection ...
Grubeck-Loebenstein, B   +115 more
core   +3 more sources

Bibliometric and visualization analysis of global research trends on immunosenescence (1970–2021)

open access: yesExperimental Gerontology, 2023
Background: Immunosenescence, the aging of the immune system, leads to a decline in the body's adaptability to the environment and plays an important role in various diseases. Immunosenescence has been widely studied in recent years. However, to date, no
Yao Tan   +7 more
doaj   +1 more source

Imaging Immunosenescence [PDF]

open access: yes, 2015
To demonstrate effects of aging visually requires a robust technique that can reproducibly detect small differences in efficiency or kinetics between groups. Investigators of aging will greatly appreciate the benefits of Amnis ImageStream technology ( www.amnis.com/), which combines quantitative flow cytometry with simultaneous high-resolution digital ...
Feng, Qian, Ruth R, Montgomery
openaire   +2 more sources

The impact of senescence-associated T cells on immunosenescence and age-related disorders

open access: yesInflammation and Regeneration, 2018
Immunosenescence is age-associated changes in the immunological functions, including diminished acquired immunity against infection, pro-inflammatory traits, and increased risk of autoimmunity.
Yuji Fukushima   +2 more
doaj   +1 more source

Immunosenescence: molecular mechanisms and diseases

open access: yesSignal Transduction and Targeted Therapy, 2023
Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms are linked to innate and adaptive immune dysfunction that accompanies aging (known as immunosenescence).
Zaoqu Liu   +9 more
doaj   +1 more source

Avian immunosenescence [PDF]

open access: yesAGE, 2005
Immunosenescence, the aging of the immune system, is well studied in humans. Mammalian immune systems become less capable of fighting pathogens and individuals become more susceptible to infection and cancer in their elder years. Little is currently published on avian immunosenescence even though avian immune function has been well characterized and ...
openaire   +2 more sources

New advances in CMV and immunosenescence. [PDF]

open access: yes, 2014
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines.
Goodrum, F.   +138 more
core   +4 more sources

Immunosenescence and Vaccination [PDF]

open access: yesImmunity & Ageing, 2005
Abstract The problems associated with the ageing immune system and vaccination were discussed recently at an international workshop at the Jenner Institute for Vaccine Research, Compton, UK, 6–7 October, 2005. This is a commentary on that session.
openaire   +3 more sources

Nutrition, diet and immunosenescence [PDF]

open access: yes, 2014
Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease.
Simon R. Carding   +10 more
core   +1 more source

Rescuing Immunosenescence via Non-Specific Vaccination [PDF]

open access: yes, 2021
Discrepancies in lifespan and healthy-life span are predisposing populations to an increasing burden of age-related disease. Accumulating evidence implicates aging of the immune system, termed immunosenescence, in the pathogenesis of multiple age-related
Alexander I. Mosa, Mosa, Alexander I.
core   +1 more source

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