Results 151 to 160 of about 29,033 (245)

Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao   +5 more
wiley   +1 more source

Before Symptoms Begin: Immune Activation in Preclinical ALS

open access: yes
Annals of Neurology, Volume 99, Issue 3, Page 588-590, March 2026.
Adriano Chiò, Andrea Calvo
wiley   +1 more source

T‐Cell Signaling Pathways, Including Exhaustion, Predominate in Unhealthy Visceral and Subcutaneous Adipose Tissues

open access: yesObesity, Volume 34, Issue 3, Page 674-685, March 2026.
ABSTRACT Objective Obesity is an imperfect correlate of metabolic health. Visceral adipose tissue (VAT) characteristics are considered determinants of poor health and subcutaneous adipose tissue (SAT) considered protective. There is a gap in knowledge regarding shared vs.
Sobha Puppala   +5 more
wiley   +1 more source

High‐Risk HPV in Men: A Hidden Threat to Public Health?

open access: yesReviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT High‐risk human papillomavirus (HR‐HPV) infection is a leading cause of several cancers, including those of the genital and oropharyngeal regions. While public health efforts have largely focused on women due to its link to cervical cancer, HPV also poses significant risks to men, particularly in the oropharyngeal regions. HR‐HPV prevalence in
Keesha L. Coker, Ethan L. Morgan
wiley   +1 more source

Seroprevalence and Risk Factors of Cystic Echinococcosis in Cattle and Buffaloes: Insights From an In‐House ELISA

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
This study reveals widespread exposure to Echinococcus granulosus in cattle and buffaloes across Punjab, Pakistan (overall seroprevalence 45.81%), with marked geographic, species, age, sex and breed‐related differences. Findings highlight high‐risk areas and support targeted, One Health–based surveillance and control strategies.
Mughees Aizaz Alvi   +10 more
wiley   +1 more source

A Meta‐Analysis on the Incidence and Associated Factors of Pulmonary Fungal Infections in Lung Cancer Patients: Evidence Predominantly From Chinese Studies in the Chinese and English Literature

open access: yesThoracic Cancer, Volume 17, Issue 6, March 2026.
This study aimed to estimate the incidence and risk factors of pulmonary fungal infections in lung cancer patients through a meta‐analysis of Chinese and English studies (up to April 2025). The findings indicated that: (1) Incidence: 14.0% (95% CI, 12.54%–15.45%); (2) Major Risk Factors: (a) Demographic: Age ≥ 60 years, male, smoking history.
Liping Deng, Rong Yu, Bei Chen
wiley   +1 more source

Immunosenescence in Human Disease: Mechanistic Insights and Therapeutic Opportunities. [PDF]

open access: yesBiomol Ther (Seoul)
Kim YI   +5 more
europepmc   +1 more source

Ageing Through the Looking‐Glass: The Different Flavours of Clonal Haematopoiesis

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
Different forms of CH share common germline and environmental risk factors and have overlapping prevalence and disease associations, suggesting common underlying ageing processes. We explore intersections of different forms of CH, clinical implications of these, and how this enhances our understanding of the biology of ageing.
Jasmine Singh   +4 more
wiley   +1 more source

The Immune‐Autonomic Interface in Aging: Baseline Immune Profile Shapes Cardiac Autonomic Response to Exercise

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
In 83 older adults, baseline lymphocyte phenotypes quantified by flow cytometry predicted the magnitude and direction of HRV shifts during a 2‐min step test and recovery. Bayesian models show that the immune landscape shapes exercise autonomic trajectories in a domain‐specific manner, revealing heterogeneity in physiological resilience.
Matías Castillo‐Aguilar   +5 more
wiley   +1 more source

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