Results 151 to 160 of about 29,033 (245)
Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications
Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao +5 more
wiley +1 more source
Before Symptoms Begin: Immune Activation in Preclinical ALS
Annals of Neurology, Volume 99, Issue 3, Page 588-590, March 2026.
Adriano Chiò, Andrea Calvo
wiley +1 more source
ABSTRACT Objective Obesity is an imperfect correlate of metabolic health. Visceral adipose tissue (VAT) characteristics are considered determinants of poor health and subcutaneous adipose tissue (SAT) considered protective. There is a gap in knowledge regarding shared vs.
Sobha Puppala +5 more
wiley +1 more source
High‐Risk HPV in Men: A Hidden Threat to Public Health?
ABSTRACT High‐risk human papillomavirus (HR‐HPV) infection is a leading cause of several cancers, including those of the genital and oropharyngeal regions. While public health efforts have largely focused on women due to its link to cervical cancer, HPV also poses significant risks to men, particularly in the oropharyngeal regions. HR‐HPV prevalence in
Keesha L. Coker, Ethan L. Morgan
wiley +1 more source
This study reveals widespread exposure to Echinococcus granulosus in cattle and buffaloes across Punjab, Pakistan (overall seroprevalence 45.81%), with marked geographic, species, age, sex and breed‐related differences. Findings highlight high‐risk areas and support targeted, One Health–based surveillance and control strategies.
Mughees Aizaz Alvi +10 more
wiley +1 more source
This study aimed to estimate the incidence and risk factors of pulmonary fungal infections in lung cancer patients through a meta‐analysis of Chinese and English studies (up to April 2025). The findings indicated that: (1) Incidence: 14.0% (95% CI, 12.54%–15.45%); (2) Major Risk Factors: (a) Demographic: Age ≥ 60 years, male, smoking history.
Liping Deng, Rong Yu, Bei Chen
wiley +1 more source
Immunosenescence in Human Disease: Mechanistic Insights and Therapeutic Opportunities. [PDF]
Kim YI +5 more
europepmc +1 more source
Ageing Through the Looking‐Glass: The Different Flavours of Clonal Haematopoiesis
Different forms of CH share common germline and environmental risk factors and have overlapping prevalence and disease associations, suggesting common underlying ageing processes. We explore intersections of different forms of CH, clinical implications of these, and how this enhances our understanding of the biology of ageing.
Jasmine Singh +4 more
wiley +1 more source
In 83 older adults, baseline lymphocyte phenotypes quantified by flow cytometry predicted the magnitude and direction of HRV shifts during a 2‐min step test and recovery. Bayesian models show that the immune landscape shapes exercise autonomic trajectories in a domain‐specific manner, revealing heterogeneity in physiological resilience.
Matías Castillo‐Aguilar +5 more
wiley +1 more source
Editorial: Immune senescence: a key driver of aging and age-related disorders. [PDF]
Luan J, Wu B, Gao X.
europepmc +1 more source

