Results 141 to 150 of about 165,216 (289)

The Immunosuppressive Agent 15-Deoxyspergualin Functions by Inhibiting Cell Cycle Progression and Cytokine Production Following Naive T Cell Activation [PDF]

, 2002
Hilda Holcombe, Ira Mellman, Charles A. Janeway, Kim Bottomly, Bonnie N. Dittel   +4 more
openalex   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

Toxoplasmosis in patients with an autoimmune disease and immunosuppressive agents: A multicenter study and literature review. [PDF]

PLoS Negl Trop Dis, 2022
Durieux MF, Lopez JG, Banjari M, Passebosc-Faure K, Brenier-Pinchart MP, Paris L, Gargala G, Berthier S, Bonhomme J, Chemla C, Villena I, Flori P, Fréalle E, L'Ollivier C, Lussac-Sorton F, Montoya JG, Cateau E, Pomares C, Simon L, Quinio D, Robert-Gangneux F, Yera H, Labriffe M, Fauchais AL, Dardé ML.   +24 more
europepmc   +1 more source

ADVANTAGES OF CYCLOSPORINE AS SOLE IMMUNOSUPPRESSIVE AGENT IN CHILDREN WITH TRANSPLANTED KIDNEYS

, 1992
Luciana Ghio, Antonio Tarantino, Alberto Edefonti, Adriana Mocciaro, Marisa Giani, Luisella Guerra, Luisa Berardinelli, A Vegeto   +7 more
openalex   +1 more source

An Anisotropic Gold‐Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy

Advanced Science, EarlyView.
A multifunctional anisotropic Au‐Pd heterostructured nanosystem is developed that incorporates a plasmonically enhanced Au‐Pd core, with a shell composed of a biodegradable, Mn‐doped targeting peptide. The nanosystem integrates photothermal, radiotherapeutic, and immunomodulatory functions.
Cheng Chen, Yuqi Huang, Wandong Wang, Minghao Chao, Weiguo Sun, Yinghui Kong, Guan Jiang, Yong Gao, Fenglei Gao   +8 more
wiley   +1 more source

Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents. [PDF]

Case Rep Pathol, 2022
Okano S, Yao T, Nomura O, Nagahara A, Hagiwara T, Sugimoto K, Takahashi M, Sakamoto K.   +7 more
europepmc   +1 more source

FK506 VERSUS CYCLOSPORINE AS PRIMARY IMMUNOSUPPRESSIVE AGENT FOR ORTHOTOPIC LIVER ALLOGRAFT RECIPIENTS HISTOLOGIC AND IMMUNOPATHOLOGIC OBSERVATIONS1

, 1993
Prodromos Hytiroglou, RICHARD LEE, Kavita Sharma, Neil D. Theise, MYRON SCHWARTZ, Charles M. Miller, Swan N. Thung   +6 more
openalex   +1 more source

Preliminary guidelines for diagnosing and treating tuberculosis in patients with rheumatoid arthritis in immunosuppressive trials or being treated with biological agents [PDF]

, 2002
D E Furst, J. Cush, Stefan H. E. Kaufmann, J. Siegel, R. Kurth   +4 more
openalex   +1 more source

Paracrine Orchestration of Tumor Microenvironment Remodeling Induced by GLO1 Potentiates Lymph Node Metastasis in Breast Cancer

Advanced Science, EarlyView.
Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie, Wenjian Liu, Xinpei Deng, Huan Wang, Xueqi Ou, Xin An, Min‐Yi Situ, Anli Yang, Chuan Peng, Rongfang He, Yi Xie, Hailin Tang, Yuman Chen, Jie‐Ying Liang, Ruonan Shao, Weikai Xiao, Shaoquan Zheng   +16 more
wiley   +1 more source

Complications Associated with Immunosuppressive Agents in Solid Organ Transplant Recipients: A Nationwide Analysis. [PDF]

J Clin Med
Lee AY, Jeong J, Heo KN, Park S, Ah YM, Han JM, Lee JY, Min SI.   +7 more
europepmc   +1 more source