Results 221 to 230 of about 1,346,069 (268)
Some of the next articles are maybe not open access.
In Vitro Models of Angiogenesis
World Journal of Surgery, 2007AbstractNeovascularization can be categorized into two general processes: vasculogenesis and angiogenesis. Angiogenesis is the formation of new capillaries from pre‐existing vessels, requiring growth factor driven recruitment, migration, proliferation, and differentiation of endothelial cells (ECs). Complex cell–cell and cell‐extracellular matrix (ECM)
Areck A, Ucuzian, Howard P, Greisler
openaire +2 more sources
Drug Safety, 1990
The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
openaire +2 more sources
The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
openaire +2 more sources
2017
Endothelial cells form a barrier between the blood and the central nervous system, namely the blood-brain barrier (BBB). Cellular components of the BBB, as well as tight junctions and paracellular barrier characterizations, are described in this chapter.
Kara, Aslı +2 more
openaire +3 more sources
Endothelial cells form a barrier between the blood and the central nervous system, namely the blood-brain barrier (BBB). Cellular components of the BBB, as well as tight junctions and paracellular barrier characterizations, are described in this chapter.
Kara, Aslı +2 more
openaire +3 more sources
1996
Pharmaceutical companies are investing time and money in the development of alternatives to injectable formulations for the systemic delivery of therapeutics. Alternative delivery systems offer enormous market potential and increased patient compliance. The nasal route has proved effective and acceptable for several therapeutics.
openaire +2 more sources
Pharmaceutical companies are investing time and money in the development of alternatives to injectable formulations for the systemic delivery of therapeutics. Alternative delivery systems offer enormous market potential and increased patient compliance. The nasal route has proved effective and acceptable for several therapeutics.
openaire +2 more sources
Building In Vitro Models of Organs
2005Tissue-engineering techniques are being used to build in vitro models of organs as substitutes for human donor organs for transplantation as well as in vitro toxicology testing (as alternatives to use of animals). Tissue engineering involves the fabrication of scaffolds from materials that are biologically compatible to serve as cellular supports and ...
Erik J, Suuronen +4 more
openaire +2 more sources
In vitro models of biocompatibility: A review
Dental Materials, 1996The objectives of this paper were to define in vitro biocompatibility of materials, to discuss some of the issues concerning why conclusions from tissue culture are sometimes different from in vivo biocompatibility, to give highlights of the sequence of the development of these in vitro assays from the early 1950s to their present state of development,
C T, Hanks, J C, Wataha, Z, Sun
openaire +2 more sources
Prototype of an in vitro model of the microcirculation
Microvascular Research, 2003We have used microfabrication technology to construct a network of microchannels, patterned after the dimensions and architecture of the mammalian microcirculation. The network is cast in transparent silicone elastomer and the channels are coated with silanated mPEG to provide lubrication.
Sergey S, Shevkoplyas +3 more
openaire +2 more sources
An in vitro model of myocardial infarction
Nature Biomedical Engineering, 2020Structural and functional changes following infarction in a human heart can be modelled with human cardiac organoids set in a hypoxic gradient and stimulated with the neurotransmitter noradrenaline.
Mills, Richard, Hudson, James
openaire +3 more sources
1981
Adenocarcinoma of the prostate is the third leading cause of death in the adult human male cancer patient, after cancers of the lung and colon/rectum. The incidence of prostatic cancer has increased by more than 25% in the last 25 years. The number of deaths from prostatic carcinoma in the U.S.A.
openaire +1 more source
Adenocarcinoma of the prostate is the third leading cause of death in the adult human male cancer patient, after cancers of the lung and colon/rectum. The incidence of prostatic cancer has increased by more than 25% in the last 25 years. The number of deaths from prostatic carcinoma in the U.S.A.
openaire +1 more source
In Vitro Models of Cutaneous Inflammation
2017The skin plays an essential role in the transmission of Lyme borreliosis since it is the first interface between the Ixodes tick and the host during the inoculation of Borrelia burgdorferi sensu lato. A better understanding of the inflammatory reaction at this location is key to develop better strategies (e.g., vaccine and diagnosis) to fight this ...
Bernard, Quentin +2 more
openaire +3 more sources