Results 151 to 160 of about 117,900,808 (282)

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das, S. M. Istiaque Hamim, Md Nazmul Hasan Zilani, Kazi Sneha Chhando, Puza Das, Md Ridoy Hossain, Md. Imtiaz, Jebin Tasmin, Roney Miah, Md. Nazmul Hasan   +9 more
wiley   +1 more source

Comparative Evaluation of Ethanolic Extracts Obtained From the Seeds of White and Black Açai Exhibit Antioxidant and Cytoprotective Activity In Vitro

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Açai seed extracts (black/white) showed antioxidant activity (black ∼30% stronger), no cytotoxicity or genotoxicity, and transient cytoprotection in normal and cancer cell lines. Black extract (200 µg/mL) inhibited colony formation without reducing cisplatin efficacy. Phenolic‐rich seed waste warrants further therapeutic study. ABSTRACT The açai fruit (
Luana França Calandrini de Azevedo, Estanislaw Tairowite Prestes Correa, Hemilly Casanova Gonçalves Soeiro, Oscar Vinícius Moraes dos Santos, Gustavo Henrique da Silva Lopes, Karina Motta Melo, Vinicius Silva de Carvalho, Andryo Orfi de Almada Vilhena, Jorge das Dores Rissino, Karen Albuquerque Dias da Costa, Alberdan da Silva Santos, Cleusa Yoshiko Nagamachi, Julio Cesar Pieczarka   +12 more
wiley   +1 more source

Differential Mutagenic Response of Rat Liver and Lung to Nicotine-Derived Nitrosamine Ketone (NNK). [PDF]

Chem Res Toxicol
Jolly RA, Noteboom J, LeBlanc DPM, Marchetti F, Cavanagh KL, Minocherhomji S.   +5 more
europepmc   +1 more source

Acorus calamus L. for Cognitive Enhancement: A Systematic Review of Its Ethnobotanical Practices and Scientific Evidence

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Acorus calamus is an important medicinal plants having a wide range of biological properties. Traditionally, the plant is commonly used to treat various diseases including fever, cold, pain and swelling, stomach problem, etc. The major compound found in the plant is β‐ asarone.
Raghu Tamang, Anindita Gogoi, Twahira Begum, Mohan Lal   +3 more
wiley   +1 more source

Cytotoxicity across OECD methods is not a single endpoint: context-dependent roles, variability and implications for decision-making. [PDF]

NAM J
Thoma T, Löhr L, Demuth P, Hambruch N, Oesch F, Landsiedel R.   +5 more
europepmc   +1 more source

In Vivo Toxicological Assessment of Corn Irrigated With Textile Wastewater: Comparative Evaluation of Biological and Hydrocyclone Enhanced Treatments

CLEAN – Soil, Air, Water, Volume 54, Issue 10, October 2026.
Biological treatment combined with hydrocyclone processing improved textile wastewater quality. Irrigation of corn with the treated effluent was followed by in vivo toxicological assessment in mice. The combined treatment reduced genotoxicity, decreased ASAT and ALAT levels, and increased SOD activity, with no significant changes in MDA levels ...
Nawres Debbabi, Tahsine Kosksi, Abir Salek, Marwa Rejeb, Arem Selmi, Tarek Baati, Leila Njim, Mouna Maatouk, Leila Chekir‐Ghedira   +8 more
wiley   +1 more source

Assessment of mutagenic potential of puberulic acid contaminated in red yeast rice (beni-koji) health food supplements. [PDF]

Mutagenesis
Sugiyama KI, Furuhama A, Horibata K, Tsuda M, Izawa K, Tsuji G, Demizu Y, Matsushita K, Toyoda T, Hirabayashi Y, Saito Y, Honma M.   +11 more
europepmc   +1 more source

Mechanisms of oxidative stress-induced in vivo mutagenicity by potassium bromate and nitrofurantoin. [PDF]

J Toxicol Pathol, 2018
Tsuchiya T, Kijima A, Ishii Y, Takasu S, Yokoo Y, Nishikawa A, Yanai T, Umemura T.   +7 more
europepmc   +1 more source

Impaired Motor Function in a Zebrafish Stathmin‐2 Knockout Model

Developmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Stathmin‐2 (STMN2) is a microtubule‐associated protein that plays a role in the stability of microtubules in axons of the nervous system of animals. In this study, we generated a novel zebrafish STMN2 knockout (KO) model. STMN2 is represented by two genes in the zebrafish genome: stmn2a and stmn2b.
Tyler J. N. Gurberg, Ziyaan A. Harji, Christian J. Rampal, Joséphine Sacy‐Richer, Amy Wang, Esteban C. Rodríguez, Gary A. B. Armstrong   +6 more
wiley   +1 more source

Complex versus simple <i>N</i>-nitrosamines: Comprehensive genotoxicity and in silico carcinogenicity assessment toward future testing paradigms. [PDF]

Sci Adv
Sun X, Schuler M, Zhang S, Kostal J, Cheung JR, Kenyon M, Watt E, Dobo K.   +7 more
europepmc   +1 more source