Melatonin/Cyclodextrin Inclusion Complexes: A Review [PDF]
Molecules, 2022 Melatonin (MLT) is involved in many functions of the human body, mainly in sleeping-related disorders. It also has anti-oxidant potential and has been proven very effective in the treatment of seasonal affective disorders (SAD), which afflict some people
Aikaterini Sakellaropoulou +2 more
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Cyclodextrins, Surfactants and Their Inclusion Complexes [PDF]
MoleculesHerein, a brief overview of the cyclodextrin structure is provided, along with its most important derivatives. The difference between the water molecules in the outer hydration shell of cyclodextrin and those in its hydrophobic cavities is discussed. The
Ana Pilipović +3 more
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Cyclodextrin Inclusion Complexes with Hydrocortisone-Type Corticosteroids [PDF]
PharmaceuticsThe hydrocortisone-type corticosteroid (HTC) group includes valuable active pharmaceutical ingredients (APIs) such as hydrocortisone, hydrocortisone acetate, cortisone acetate, tixocortol pivalate, prednisolone, methylprednisolone, and prednisone ...
Aleksandra Kowalska, Łukasz Szeleszczuk
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Preparation and Characterisation of Zinc Diethyldithiocarbamate–Cyclodextrin Inclusion Complexes for Potential Lung Cancer Treatment [PDF]
Pharmaceutics, 2023 Zinc diethyldithiocarbamate (Zn (DDC)2), a disulfiram metabolite (anti-alcoholism drug), has shown a strong anti-cancer activity in vitro. However, its application was limited by its low aqueous solubility and rapid metabolism.
Ayşe Kaya +6 more
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Simazine inclusion complexes with cucurbiturils (n = 6–8): experimental and molecular dynamics studies [PDF]
Scientific ReportsSimazine (SIM) inclusion complexes with cucurbit[n]uril, CBn, (n = 6–8), have been studied in both aqueous solutions and solid states. NMR measurements were taken in DMSO.
Abdalla A. Elbashir +3 more
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Development of essential oils inclusion complexes: a nanotechnology approach with enhanced thermal and light stability [PDF]
Discover NanoEssential oils (EOs) are volatile compounds that may have antimicrobial and antioxidant properties. Despite their potential application, low water solubility and chemical instability are limiting factors.
Fernanda Ramalho Procopio +6 more
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Characterization and In Vitro Prebiotic Activity of Pterostilbene/β-Cyclodextrin Inclusion Complexes [PDF]
MoleculesPterostilbene (PTS) has multiple benefits, but poor water solubility and bioavailability limit its application. PTS/β-CD inclusion complexes were synthesized through the phase solubility method to enhance their water solubility.
Chuan-Chao Wu +6 more
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Formulation and Characterization of β-Cyclodextrins–Nitazoxanide Inclusion Complexes: Enhanced Solubility, In Vitro Drug Release, and Antiviral Activity in Vero Cells [PDF]
PharmaceuticsBackground/Objectives: Nitazoxanide (NTX) exhibits promising therapeutic potential; its effectiveness is constrained by its low oral bioavailability due to its poor water solubility and limited permeability.
Kuppu Sakthi Velu +5 more
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Preparation of orally disintegrated membranes from liquorice inclusion complexes [PDF]
BIO Web of Conferences, 2023 Objective: to prepare and evaluate orally disintegrating films of liquorice inclusion complexes. Methods: the active components of Chinese liquorice were extracted by pressurised extraction technique, and the inclusion complexes were prepared by ...
Chen Lei +5 more
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Frontiers in Nutrition, 2022 Background: Allyl isothiocyanate is an excellent antimicrobial compound that has been applied in the development of active food packaging materials in the last years. However, the high volatility of this compound could prevent a lasting effect over time.
Cristina Muñoz-Shugulí +16 more
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