Results 191 to 200 of about 134,979 (258)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Coumarin/β-Cyclodextrin Inclusion Complexes Promote Acceleration and Improvement of Wound Healing. [PDF]

ACS Appl Mater Interfaces
Dutra FVA, Francisco CS, Carneiro Pires B, Borges MMC, Torres ALH, Resende VA, Mateus MFM, Cipriano DF, Miguez FB, Freitas JCC, Teixeira JP, Borges WS, Guimarães L, da Cunha EFF, Ramalho TC, Nascimento CS, De Sousa FB, Costa RA, Lacerda V, Borges KB.   +19 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Photoinduced Electron Transfer in Inclusion Complexes of Carbon Nanohoops. [PDF]

Acc Chem Res
Stasyuk OA, Voityuk AA, Stasyuk AJ, Solà M.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Release and Disintegration Properties of Poly(lactic Acid) Films with Allyl Isothiocyanate-β-Cyclodextrin Inclusion Complexes for Active Food Packaging. [PDF]

Molecules
Muñoz-Shugulí C, Rodríguez-Mercado F, Guarda A, Galotto MJ, Jiménez A, Garrigós MC, Ramos M.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile Acid Levels. [PDF]

Molecules
Yoshikiyo K, Shimizu H, Nagato EG, Ishizuka S, Yamamoto T.   +4 more
europepmc   +1 more source

Optimal <i>st</i>-PMMA/C₆₀ helical inclusion complexes via tunable energy landscapes for the application of an Ag SERS-active substrate. [PDF]

J Appl Crystallogr
Tsai SY, Tseng WT, Su JH, Wang YH, Chang YW, Wang CH, Jeng US, Wu KY, Wang CL, Chuang WT.   +9 more
europepmc   +1 more source

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Inclusion complexes of coumarin in cucurbiturils

Organic & Biomolecular Chemistry, 2009
Coumarin was found to form stable inclusion complexes with cucurbiturils. In the presence of cucurbit[7]uril (CB[7]), 1 : 1 inclusion complexes were observed in aqueous solution, as monitored by (1)H NMR and UV-visible absorption spectroscopies, and further supported by ab initio calculations, whereas with cucurbit[8]uril (CB[8]) a solid phase 1 : 2 ...
Wang, Ruibing, Bardelang, David, Waite, M´elanie, Udachin, Konstantin A., Leek, Donald M., Yu, Kui, Ratcliffe, Christopher I., Ripmeester, John A.   +7 more
openaire   +3 more sources