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Fasting GLP-1 Levels in Women with PCOS and CAH
Acta Medica BulgaricaPolycystic ovarian syndrome (PCOS) is the most prevalent condition associated with increased androgens, but some rare diseases, e.g., congenital adrenal hyperplasia (CAH), should also be considered in the differential diagnosis of hyperandrogenemia.
Robeva R. +3 more
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Incretin Hormones and Type 2 Diabetes—Mechanistic Insights and Therapeutic Approaches
Biology, 2020 Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted from the gut upon nutrient stimulation and regulate postprandial metabolism.
Geke Aline Boer, Jens Juul Holst
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Life, 2023 The consumption of artificial and low-calorie sweeteners (ASs, LCSs) is an important component of the Western diet. ASs play a role in the pathogenesis of metabolic syndrome, dysbiosis, inflammatory bowel diseases (IBDs), and various inflammatory ...
Edit Posta +5 more
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Understanding the Incretin Effect [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2011 It is well known that the incretin effect contributes as much as half of the insulin secretory response to oral glucose load and that this effect is reduced along with worsening glucose tolerance in those with type 2 diabetes. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the two primary incretin hormones secreted from ...
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Diabetes, Metabolic Syndrome and Obesity, 2018 Anne J Kugler,1 Michael L Thiman2 1Department of Pharmacy Practice and Administration, Western University of Health Sciences College of Pharmacy, Pomona, CA, USA; 2Department of Clinical and Administrative Pharmacy, University of Georgia College of ...
Kugler AJ, Thiman ML
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Pharmalogical effects and results of clinical trials of the first incretinomimetic exenatide
Сахарный диабет, 2011 The review is devoted to the pharmacological effects, the results of clinical trials, safety and the research perspectives of the first incretinomimetic ...
Alexander Sergeevich Ametov +1 more
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Pathogenesis of type 2 diabetes in Japan and East Asian populations: Basic and clinical explorations
Proceedings of the Japan Academy. Series B, Physical and Biological SciencesIt is now accepted that the pathogenesis of type 2 diabetes in East Asians including Japanese differs distinctly from that in Caucasians. Many non-obese individuals in Japan develop type 2 diabetes and present clinically with insufficient insulin ...
Yutaka SEINO, Yuji YAMAZAKI
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First GLP-1 analog liraglutide: the result of clinical trails on efficacy
Сахарный диабет, 2011 This review analytically considers the results of clinical trials on efficacy and safety and clinical perspectives of GLP-1 analog ...
Alexander Sergeevich Ametov +1 more
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Frontiers in EndocrinologyBackgroundHormonal and metabolic responses to high protein intake are not well understood. The aims of this study were to compare the metabolic and hormonal responses to isocaloric intakes of whey protein alone versus carbohydrate alone. Additionally, we
Matthieu Clauss +6 more
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The incretin concept today [PDF]
Diabetologia, 1979 1. The insulinogenic factor of the gastrointestinal mucosa named "incretin" is only one part of the complex enteroinsular axis. --2. Of the chemically defined gastrointestinal hormones GIP is the strongest incretin candidate. --3. Because of the dual function of GIP as gastrone and insulinotropic substance several safeguards against GIP-mediated ...
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