Results 11 to 20 of about 8,656 (193)
Pleiotropic effects of incretins
Indian Journal of Endocrinology and Metabolism, 2012 Drugs that augment the incretin system [glucagon like peptide (GLP) agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors] represent a novel class of anti-hyperglycemic agents that have shown to improve the health and survival of beta-cells (improvement
Vishal Gupta
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Incretins or Anti-Incretins? A New Model for the “Entero-Pancreatic Axis” [PDF]
Hormone and Metabolic Research, 2014 The role of incretins in glucose homeostasis is well known. Yet, in recent years, the sustained weight loss and rapid glycemic control following bariatric surgery has challenged our understanding of the intestinal-pancreatic interaction. This in turn led to the introduction of metabolic surgery, an innovative medical discipline in which a surgical ...
Kamvissi, V +4 more
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Orvosi Hetilap, 2011 The discovery of incretins − glucagon-like peptide (GLP)-1 and glucose-dependent insulinotrop peptide (GIP) −, clarification of their physiological properties as well as therapeutic application of incretin-based blood glucose lowering drugs opened new perspectives in the medical management of type 2 diabetes.
Gábor Winkler
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Bile acids and incretins as modulators of obesity-associated atherosclerosis [PDF]
Frontiers in Cardiovascular MedicineObesity is one of the major global health concerns of the 21st century, associated with many comorbidities such as type 2 diabetes mellitus (T2DM), metabolic dysfunction-associated steatotic liver disease, and early and aggressive atherosclerotic ...
Andrijana Kirsch +4 more
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12-month effects of incretins versus SGLT2-Inhibitors on cognitive performance and metabolic profile. A randomized clinical trial in the elderly with Type-2 diabetes mellitus [PDF]
Clinical Pharmacology: Advances and Applications, 2018 Simone Perna,1 Manuela Mainardi,2 Paolo Astrone,2 Carlotta Gozzer,3 Anna Biava,1 Ruben Bacchio,3 Daniele Spadaccini,3 Sebastiano Bruno Solerte,2 Mariangela Rondanelli4 1Department of Biology, College of Science, University of Bahrain, Sakhir Campus ...
Perna S +8 more
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Pleiotropic effects of incretins and antidiabetics with incretine mechanism
Orvosi Hetilap, 2013 Discovery of physiological and pharmacological characteristics of incretins (glucagon-like peptide-1 and glucose-dependent insulinotrop polypeptide), and the introduction of various products of those into the clinical practice has fundamentally changed blood glucose lowering therapy in type 2 diabetes.
Winkler, Gábor
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To be or not to be—an incretin or enterogastrone? [PDF]
Gut, 2006 Glucagon-like peptide 1 does not comfortably fulfil the criterion of a gut derived factor responsible for an enhanced meal related insulin response; it appears logical to add the definition of a "physiological incretin hormone".
Horowitz, M., Nauck, M.
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Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism [PDF]
, 2022 Objective: Incretins are known to influence lipid metabolism in the intestine when administered as pharmacologic agents. The aggregate influence of endogenous incretins on chylomicron production and clearance is less clear, particularly in light of ...
Hartmann, Bolette +17 more
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Incretin‐based therapies [PDF]
Journal of Diabetes, 2012 AbstractIncretin‐based therapies have established a foothold in the diabetes armamentarium through the introduction of oral dipeptidyl peptidase‐4 inhibitors and the injectable class, the glucagon‐like peptide‐1 receptor agonists. In 2009, the American Diabetes Association and European Association for the Study of Diabetes authored a revised consensus ...
Stonehouse, Anthony H +2 more
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Frontiers in Cell and Developmental Biology, 2021 Enteroendocrine cells directly integrate signals of nutrient content within the gut lumen with distant hormonal responses and nutrient disposal via the production and secretion of peptides, including glucose-dependent insulinotropic polypeptide (GIP ...
Nadya M. Morrow +7 more
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