Results 11 to 20 of about 8,133 (247)
Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism [PDF]
, 2022 Objective: Incretins are known to influence lipid metabolism in the intestine when administered as pharmacologic agents. The aggregate influence of endogenous incretins on chylomicron production and clearance is less clear, particularly in light of ...
Hartmann, Bolette +17 more
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The physiology of incretins [PDF]
, 2011 The discovery of incretins − glucagon-like peptide (GLP)-1 and glucose-dependent insulinotrop peptide (GIP) −, clarification of their physiological properties as well as therapeutic application of incretin-based blood glucose lowering drugs opened new ...
Gábor Winkler
core +3 more sources
Scientific Reports, 2022 It has not been elucidated whether incretins affect insulin clearance in type 2 diabetes (T2D). We aimed exploring possible associations between insulin clearance and endogenously secreted or exogenously administered incretins in T2D patients. Twenty T2D
Andrea Tura +4 more
doaj +1 more source
Incretins, pregnancy, and gestational diabetes [PDF]
, 2016 The number of pregnant women affected by gestational diabetes mellitus (GDM) is increasing among Caucasians, and East Asians. GDM also increases the risk for later advent of type 2 diabetes mellitus (T2DM), obesity, and cardiovascular disease in both ...
Nikolic D. +9 more
core +3 more sources
Asian Subpopulations May Exhibit Greater Cardiovascular Benefit from Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A Meta-Analysis of Cardiovascular Outcome Trials [PDF]
Diabetes & Metabolism Journal, 2019 BackgroundBased on reported results of three large cardiovascular outcome trials (CVOTs) of glucagon-like peptide 1 receptor agonists (GLP-1 RAs), we aimed to investigate the overall effect of GLP-1 RAs on major adverse cardiovascular events (MACEs) and ...
Yu Mi Kang +8 more
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2012 Nutrient excess results in systemic inflammation in diabetes contributing to insulin resistance, dyslipidaemia and increased cardiovascular risk. GLP-1 agonists and DPP-4 inhibitors, which are now well accepted therapies for diabetes may play a unique ...
Amitabh Hatwal
doaj +1 more source
Metformin in prediabetes: key mechanisms for the prevention of diabetes and cardiometabolic risks
Медицинский совет, 2022 Today, prediabetes is regarded by the world medical community as early diabetes mellitus. The accumulated research evidence shows that prediabetes is characterized by a spectrum of complications that are similar to those of diabetes mellitus, which means
A. Yu. Babenko
doaj +1 more source
Cell Reports, 2014 Incretins, hormones released by the gut after meal ingestion, are essential for maintaining systemic glucose homeostasis by stimulating insulin secretion.
Ghupurjan Gheni +21 more
doaj +1 more source
Frontiers in Endocrinology, 2021 ObjectiveWe aimed to investigate insulin-, mTOR- and SGK1-dependent signaling basal states in morbidly obese patients’ fat. We analyzed the correlation between the signaling activity, carbohydrate metabolism, and incretin profiles of patients.MethodsThe ...
Iurii Stafeev +21 more
doaj +1 more source