Results 71 to 80 of about 2,197 (174)

First Reported Nosocomial Outbreak Of NDM-5-Producing Klebsiella pneumoniae In A Neonatal Unit In China

Infection and Drug Resistance, 2019
Ziyan Kong,1,* Rui Cai,1,* Chen Cheng,1 Chuanling Zhang,2 Haiquan Kang,3 Ping Ma,3 Bing Gu1,3 1Medical Technology School, Xuzhou Medical University, Xuzhou, Jiangsu Province, People’s Republic of China; 2Department of Laboratory Medicine, XuZhou ...
Kong Z, Cai R, Cheng C, Zhang C, Kang H, Ma P, Gu B   +6 more
doaj  

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

VirBR counter-silences HppX3 to promote conjugation of bla NDM-IncX3 plasmids

Nucleic Acids Research
Abstract New Delhi metallo-β-lactamases (NDM), encoded by the blaNDM gene, mediate carbapenem resistance, posing serious threats to public health due to their global presence across diverse hosts and environments. The blaNDM is prominently carried by the IncX3 plasmid, which encodes a Type IV secretion system (T4SS) responsible for ...
Yuan Gao, Ning Xie, Tengfei Ma, Chun E Tan, Zhuo Wang, Rong Zhang, Shizhen Ma, Zhaoju Deng, Yang Wang, Jianzhong Shen   +9 more
openaire   +2 more sources

Epidemiological and Genomic Characteristics of blaCTX-M and blaNDM‐Producing K. pneumoniae From Dairy Cows in Henan Province, China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Extended‐spectrum β‐lactamase (ESBL) and carbapenemase‐producing Klebsiella spp., particularly K. pneumoniae, are emerging threats in both clinical and community settings. To investigate the epidemiology, phylogenetics, and antimicrobial resistance of bovine‐origin strains, 174 bacterial isolates were obtained from 180 mastitic milk samples across ...
Yiming Feng, Wenfeng Li, Mengjuan Ma, Yajun Zhai, Hua Wu, Jianhua Liu, Gongzheng Hu, Dandan He, Yushan Pan, Zhong Peng   +9 more
wiley   +1 more source

Emergence of IncX3 Plasmid-Harboring blaNDM–5 Dominated by Escherichia coli ST48 in a Goose Farm in Jiangsu, China [PDF]

Frontiers in Microbiology, 2019
Twelve carbapenem-resistant Escherichia coli strains were obtained from goose farms in Jiangsu, China. These isolates were resistant to multiple antimicrobials, and positive for the blaNDM–5. The carbapenem-resistance of all strains mediated by blaNDM–5 were successfully conjugated to E. coli J53.
Ziyi Liu, Ziyi Liu, Xia Xiao, Xia Xiao, Xia Xiao, Yan Li, Yan Li, Yuan Liu, Yuan Liu, Yuan Liu, Ruichao Li, Ruichao Li, Ruichao Li, Zhiqiang Wang, Zhiqiang Wang, Zhiqiang Wang, Zhiqiang Wang   +16 more
openaire   +3 more sources

First Report of OXA-181-Producing Enterobacterales Isolates in Latin America

Microbiology Spectrum, 2023
We characterized five carbapenemase-producing Enterobacterales (CPE) isolates from two health care institutions in Lima, Peru. The isolates were identified as Klebsiella pneumoniae (n = 3), Citrobacter portucalensis (n = 1), and Escherichia coli (n = 1).
Diego Cuicapuza, Luis Alvarado, Norah Tocasca, Daniel Aguilar, Juan Carlos Gómez-de-la-Torre, Guillermo Salvatierra, Pablo Tsukayama, Jesús Tamariz   +7 more
doaj   +1 more source

Companion Animals Harbour Globally Circulating Human‐Associated Klebsiella pneumoniae Lineages and High‐Risk Antimicrobial Resistance Clones

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Companion animals are increasingly recognised within One Health antimicrobial‐resistance (AMR) surveillance, yet the global genomic structure of dog‐ and cat‐associated Klebsiella pneumoniae remains poorly defined. We assembled a global dataset of 712 domestic dog (Canis lupus familiaris)– and cat (Felis catus)–derived K.
Stephen Mark Edward Fordham, Elizabeth Sheridan, Francis Drobniewski, Wanjiang Zhang   +3 more
wiley   +1 more source

This is the Fig 2 Location of the bla_NDM-1 gene and the IncX3 type of bla_NDM-1 plasmid.

, 2015
This is the Fig 2 Location of the blaNDM-1 gene and the IncX3 type of blaNDM-1 plasmid.
Xiaoxing Du (750398), Yuqin Shen (750399), Qing Yang (67856), Lanfang Fang (750397), Yunsong Yu (496103), Ying Fu (173963)   +5 more
core   +1 more source

Understanding the Association of Plasmid Incompatibility Groups With Variable Antimicrobial Resistance Genotypes in Bacteria

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Multi‐replicon plasmids, particularly those belonging to the IncF, IncI, and IncH families, act as major vectors of antimicrobial resistance genes. Although no clear association was found between incompatibility groups and specific antibiotic classes, plasmids with more replicons exhibited higher resistance potential, highlighting their role in AMR ...
Hannay Crystynah Almeida de Souza, Pedro Panzenhagen, Anamaria Mota Pereira dos Santos, Ana Beatriz Portes, Arlen Carvalho de Oliveira Almeida, Carlos Adam Conte Junior   +5 more
wiley   +1 more source

Genomic characterisation of blaNDM-5-IncX3 plasmid in an ST4 Klebsiella aerogenes clinical isolate

Journal of Global Antimicrobial Resistance
The dissemination of New Delhi metallo-β-lactamase-5 (NDM-5) among various species of Enterobacterales has attracted serious global attention. Here, we characterise the genomic characterisation of blaNDM-5-IncX3 plasmid (pNDM-KA3) in an ST4 Klebsiella aerogenes (KA3) strain isolated from a neonate with pneumonia.Antimicrobial susceptibility and ...
Fen Pan, Qi Xu, Cong Jiang, Qingqing Du, Fangyuan Yu, Pengcheng Chen, Hong Zhang   +6 more
openaire   +3 more sources