Results 71 to 80 of about 2,171 (161)

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source

Unraveling Genetic Diversity and Antibiotic Resistance Mechanisms in Citrobacter freundii Isolates From Meat Products: Implications for Food Safety and Public Health

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
This study highlights the high prevalence and multidrug resistance of Citrobacter freundii in poultry meat, revealing diverse genotypes and key resistance mechanisms through integrated molecular diagnostics and clustering analysis. A graphical abstract summarising the main findings and methodology of this study is provided as a separate file ...
Hussein Khodabandeh, Elaheh Tajbakhsh, Faham Khamesipour, Hassan Momtaz, Manochehr Momeni shahraki   +4 more
wiley   +1 more source

Genomic Characterization of Pan‐Drug Resistant Klebsiella pneumoniae KPNW Isolated From UTI Patient in Bangladesh

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
Klebsiella pneumoniae isolate KPNW showed resistance to all clinically relevant antibiotics. Upon whole genome sequencing and characterization, we detected a large number of antimicrobial resistance genes, resistance‐associated point mutations, virulence determinants, heavy metal resistance genes, and mobile genetic elements in errorits genome ...
Md. Wahid Murad, G. M. Shah Poran, Kalpana Baidya, Nazmul Ahsan   +3 more
wiley   +1 more source

bla NDM-5 carried by a hypervirulent Klebsiella pneumoniae with sequence type 29

Antimicrobial Resistance and Infection Control, 2019
Background A carbapenem-resistant hypermucoviscous Klebsiella pneumoniae isolate was recovered from human sputum. Methods Whole genome sequencing of this isolate was carried out to reveal its clonal background, antimicrobial resistance determinants and ...
Yi Yuan, Ying Li, Guangxi Wang, Chengwen Li, Yung-Fu Chang, Wenbi Chen, Siji Nian, Yingyu Mao, Jinping Zhang, Fangcai Zhong, Luhua Zhang   +10 more
doaj   +1 more source

Global Increase of Antibiotic Resistance Genes in Conjugative Plasmids [PDF]

, 2023
Antibiotic resistance is propagating worldwide, but the predominant dissemination mechanisms are not fully understood. Here, we report that antibiotic resistance gene (ARG) abundance in conjugative plasmids that are recorded in the National Center for ...
Alvarez, Pedro J. J., Long, Xiang, Luo, Yi, Mao, Daqing, Ren, Hongqiang, Wang, Xiaolong, Xu, Ximing, Zhang, Hanhui   +7 more
core   +3 more sources

Study on Antibacterial Activity of Water Extract of Galla chinensis Against Carbapenemase‐Producing Enterobacteriaceae

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Galla chinensis is an eco‐friendly and effective alternative to traditional antibiotics for combating multidrug resistance. ABSTRACT Carbapenemase‐producing Enterobacteriaceae (CPE) represents a significant global public health concern, largely driven by factors including misuse of antibiotics and their inappropriate use in livestock.
MinHui Miao, Jiayao Lin, Jie Zhu, Hong Du, Di Mei, AnQi Gu, BeiNa Hu, HaiQiang Jiang   +7 more
wiley   +1 more source

Clinical and Microbiological Characteristics of a Community-Acquired Carbapenem-Resistant Escherichia coli ST410 Isolate Harbouring blaNDM-5-Encoding IncX3-Type Plasmid From Blood

Frontiers in Medicine, 2021
Objectives: The aim of this research was to investigate the clinical and microbiological characteristics of a case of community-acquired carbapenem-resistant Escherichia coli isolated from a patient with a bloodstream infection in China.Methods ...
Ji-Na Gu, Lin Chen, Xing-Bei Weng, Xiao-Yan Yang, Dan-Mei Pan   +4 more
doaj   +1 more source

Occurrence and spread of carbapenemase‐producing Enterobacterales (CPE) in the food chain in the EU/EFTA. Part 1: 2025 update

EFSA Journal, Volume 23, Issue 4, April 2025.
Abstract Carbapenemase‐producing Enterobacterales (CPE) have been reported in the food chain in 14 out of 30 EU/EFTA countries. Commonly reported genes are blaVIM‐1, blaOXA‐48 and blaOXA‐181, followed by blaNDM‐5 and blaIMI‐1. Escherichia coli, target of most of the studies, Enterobacter cloacae complex, Klebsiella pneumoniae complex and Salmonella ...
EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), Ana Allende, Avelino Álvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Fernando Pérez‐Rodríguez, Panagiotis Skandamis, Elisabetta Suffredini, Hector Argüello, Johan Bengtsson‐Palme, Alessandra Carattoli, Anke Kohlenberg, Dominique L. Monnet, Laurent Poirel, Beatriz Guerra, Raquel García‐Fierro, Ernesto Liébana, Sonagnon Martin Goudjihounde, Núria Ferrer‐Bustins, Hanne Rabbås, Luisa Peixe   +28 more
wiley   +1 more source

Environmental dissemination of carbapenemase-producing Enterobacteriaceae in rivers in Switzerland [PDF]

, 2020
The aquatic environment takes on a key role in the dissemination of antimicrobial-resistant Enterobacteriaceae. This study assesses the occurrence of carbapenemase-producing Enterobacteriaceae (CPE) in freshwater samples from rivers, inland canals, and ...
Bleichenbacher, Stephanie, Endimiani, Andrea, Nüesch-Inderbinen, Magdalena, Perreten, Vincent, Stephan, Roger, Stevens, Marc J A, Zurfluh, Katrin   +6 more
core   +1 more source

Genomic Characterization of NDM‐1 Harboring Extensively‐Drug Resistance Klebsiella pneumoniae Isolate From ICU‐Admitted Patient With COVID‐19

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Currently, carbapenem‐resistant Klebsiella pneumoniae (CR‐KP) strains, particularly those producing New Delhi metallo‐beta‐lactamase (NDM), are increasingly recognized as a significant threat to global health. The present study aimed to conduct a genomic analysis of an NDM‐1‐producing CR‐KP strain isolated from patients with coronavirus disease of 2019
Abolfazl Rafati Zomorodi, Himen Salimizand, Niloufar Mohseni, Maryam Hafiz, Helia Nikoueian, Tahereh Gholamhosseini-Moghaddam, Fatemeh Aflakian, Amitis Ramezani   +7 more
wiley   +1 more source