Results 61 to 70 of about 4,853 (196)

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Optimization of indirubin and indigo production in E.coli [PDF]

, 2015
The goal of this thesis is to determine the conditions that give the highest yield of indigo and indirubin in recombinant E.coli. This E.coli has been transformed with a P450 gene from woad, an indigo producing plant. The conditions investigated were the
Cairo, Gisela
core   +1 more source

Natural compounds for pediatric cancer treatment [PDF]

, 2015
There is a tremendous need in clinics to impair cancer progression through noninvasive therapeutic approaches. The use of natural compounds to achieve this is of importance to improve the quality of life of young patients during their treatments.
Boffa, I, De Masi, G, Ferrucci, V, Zollo, M.   +3 more
core   +1 more source

Indirubin derivatives: a patent review (2010 – present)

Expert Opinion on Therapeutic Patents, 2015
Indirubins are bisindole alkaloids naturally occurring in indigo-bearing plants or in mollusks from the Muricidae family. They belong to the rather small family of indigoids, which has nevertheless found an extreme importance in the fields of dyes and medicinal chemistry.
Gaboriaud-Kolar, N., Vougogiannopoulou, K., Skaltsounis, A.-L.   +2 more
openaire   +3 more sources

Structural Characterization and Antioxidant Activity of Polysaccharides From Indigo Naturalis Ophiopogon japonicus: Effects of Processing and Extraction Methods

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Indigo naturalis processing significantly increased polysaccharide and uronic acid content, altered monosaccharide composition, and introduced high‐molecular‐weight fractions. Structural changes enhanced DPPH and superoxide anion scavenging activities, especially in reflux‐extracted processed samples (W‐IP, IC50 = 3.19 mg/mL).
Yi Zhao, Yi Zhong, Qi Zheng, Chun‐Yan Yin, Jia‐Li Cai, Di‐Jun Wang, Li Zhu, Ji Cao, Xiao‐Jing Yan, Yuan‐Pei Lian   +9 more
wiley   +1 more source

The Potential Use of Organically Grown Dye Plants in the Organic Textile Industry: Experiences and Results on Cultivation and Yields of Dyers Chamomile (Anthemis tinctoria L.), Dyers Knotweed (Polygonum tinctorium Ait.) and Weld (Reseda luteola L.) [PDF]

, 2003
The organic cultivation of dye plants for the certified natural textiles industry is an emerging and promising sector of organic farming. In 1999 a field trial was done with different provenances of Dyer’s Chamomile (Anthemis tinctoria L.), Dyer’s ...
Hartl, A., Vogl, C.R.
core   +1 more source

Atlas‐Based Mapping of Traditional Chinese Medicine Effects on Tumor Microcirculation Regulation

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Tumor microcirculation plays a central role in the onset and progression of hypoxia, therapeutic resistance, and immune evasion within the tumor microenvironment. Traditional Chinese Medicine (TCM), characterized by its multi‐targeted and systemic regulatory properties, has garnered increasing attention for its potential to modulate
I Ho, Yijie Xie, Zhipeng Liu, Dingjun Cai   +3 more
wiley   +1 more source

The Ah receptor: adaptive metabolism, ligand diversity, and the xenokine model [PDF]

, 2020
Author Posting. © American Chemical Society, 2020. This is an open access article published under an ACS AuthorChoice License. The definitive version was published in Chemical Research in Toxicology, 33(4), (2020): 860-879, doi:10.1021/acs.chemrestox ...
Avilla, Mele N., Bradfield, Christopher A., Hahn, Mark E., Malecki, Kristen M. C., Wilson, Rachel H.   +4 more
core   +1 more source

GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins [PDF]

Chemistry & Biology, 2003
Gastropod mollusks have been used for over 2500 years to produce the "Tyrian purple" dye made famous by the Phoenicians. This dye is constituted of mixed bromine-substituted indigo and indirubin isomers. Among these, the new natural product 6-bromoindirubin and its synthetic, cell-permeable derivative, 6-bromoindirubin-3'-oxime (BIO), display ...
Meijer, L., Skaltsounis, A. L., Magiatis, P., Polychronopoulos, P., Knockaert, M., Leost, M., X. P., Ryan, C. A., Vonica, Brivanlou, A., Dajani, R., Crovace, C., Tarricone, C., Musacchio, A., S. M., Roe, Pearl, L., Greengard, P.   +15 more
openaire   +4 more sources

Bioinspired Light‐Driven Organic Rotary Molecular Systems

ChemistryEurope, Volume 4, Issue 1, January 2026.
This review explores the evolution of bioinspired light‐driven rotary molecular systems (RMSs), highlighting the integration of natural chromophore‐based fragments to enhance quantum efficiency, photostability, and biocompatibility. Key strategies to optimize photochemical performance and broaden functional applications are discussed, providing a ...
Lidia Hortigüela, Sara P. Morcillo
wiley   +1 more source