Results 61 to 70 of about 429,874 (275)

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu   +2 more
wiley   +1 more source

Investigations of Natural Products from Bryozoa Inhabiting Aotearoa New Zealand [PDF]

open access: yes, 2012
Two species of bryozoa, Pterocella vesiculosa and Plumatella repens, were investigated in an endeavour to isolate and characterise novel secondary metabolites.
Andersen, Aaron John Christian
core  

Unified Approach for the Synthesis of Close Analogues of Reverse‐Prenylated Hexahydropyrrolo Indole Alkaloids

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A simple, modular, and unified strategy for the synthesis of reverse‐prenylated hexahydropyrrolo indole alkaloids has been developed. An unusual retrosynthetic disconnection allows for the late introduction of a side chain, which distinguishes many members of this class of natural products.
Daniel Schmelzer   +2 more
wiley   +1 more source

Indole Alkaloids from Chaetomium globosum

open access: yes, 2015
Two new indole alkaloids chaetocochin J (1) and chaetoglobinol A (8), along with chetomin (2), chetoseminudin A (3), cochliodinol (9), and semicochliodinol (10), were isolated from the rice culture of the fungus Chaetomium globosum. Their structures were
Wu, Lin-Wei   +7 more
core   +1 more source

Secondary Metabolites from Rubiaceae Species

open access: yesMolecules, 2015
This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae,
Daiane Martins, Cecilia Veronica Nunez
doaj   +1 more source

Bioactive monoterpene indole alkaloids from Nauclea officinalis.

open access: yesBioorganic chemistry (Print), 2019
Two new monoterpene indole alkaloids, naucleaoffines A (1) and B (2), together with six known alkaloids (3-8), were isolated from the stems and leaves of Nauclea officinalis.
Yan-Ping Liu   +7 more
semanticscholar   +1 more source

Gold‐Catalyzed Cyclization of Indole‐Tethered Alkynes Enabling Synthesis of Exocyclic Alkenyl Tetrahydrocarbazoles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei   +4 more
wiley   +1 more source

The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids

open access: yesJournal of Natural Products, 2020
Two separate commercial products of kratom [Mitragyna speciosa (Korth.) Havil. Rubiaceae] were used to generate reference standards of its indole and oxindole alkaloids.
L. Flores-Bocanegra   +9 more
semanticscholar   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Chemical constituents and antiplasmodial activity of indole alkaloids from ochrosia oppositifolia / Mehran Fadaei Nasab [PDF]

open access: yes, 2012
The chemical constituents of Ochrosia oppositifolia have been studied. The compounds were extracted from the bark and leaves of this plant by using n-hexane,dichloromethane and methanol as solvents.
Nasab, Mehran Fadaei
core  

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