Results 81 to 90 of about 429,874 (275)

1H and 13C-NMR Data of the Simplest Plumeran Indole Alkaloids Isolated from Aspidosperma Species

open access: yesMolecules, 2012
Indole alkaloids are the chemotaxonomic markers of the Aspidosperma genera. Those that have the simplest plumeran skeleton are classified as the precursors of biosynthetic routes and the intermediates for several synthetic reactions.
Heloisa Alves Guimarães   +2 more
doaj   +1 more source

Exploration of Indole Alkaloids from Marine Fungus Pseudallescheria boydii F44-1 Using an Amino Acid-Directed Strategy

open access: yesMarine Drugs, 2019
The composition of the culture medium has great influence on the metabolite production of the marine fungus Pseudallescheria boydii F44-1. By adding amino acids to GPY culture medium, two new bisindole alkaloids, pseudboindoles A and B (1 and 2 ...
Mei-Xiang Yuan   +7 more
semanticscholar   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Bioactive Chemicals of Importance in Endophyte-Infected Grasses [PDF]

open access: yes, 2009
Janthitrems are believed to be involved in the observed sporadic cases of AR37- infected perennial ryegrass staggers. Investigations into the role of janthitrems in perennial ryegrass staggers are difficult as isolation of the compounds from the ryegrass
Babu, Jacob
core  

Gramine Suppresses Myofibroblast Activation and ECM Accumulation in Renal Fibrosis by Targeting the NF‐κB/NLRP3 and TGF‐β1/Smad Pathways

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is driven by persistent inflammation and progressive fibrosis, leading to irreversible renal damage. Gramine (GMN), an indole alkaloid, has broad pharmacological benefits. However, its therapeutic potential against renal fibrosis remains unexplored.
Shobhit Gairola   +3 more
wiley   +1 more source

Synthesis of Marine Indole Alkaloids from

open access: yesNatural Product Communications, 2008
Brominated natural indoles are frequently reported metabolites of marine seaweeds. The bryozoan Flustra foliacea has been a rich source of brominated indole alkaloids bearing prenyl or isoprenyl substituents at various positions.
Martha S. Morales-Ríos   +1 more
doaj   +1 more source

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

open access: yesMolecules, 2008
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj   +1 more source

Two New Indole Alkaloids from Toad Venom of Bufo bufo gargarizans

open access: yesMolecules, 2020
Two new indole alkaloids, Bufotenidine B (2) and Bufocarboline A (6), along with seven known indole alkaloids (1, 3–5, and 7–9) and three organic acids (10–12), were isolated from the water extract of toad venom.
Yu-Lin Chen   +8 more
doaj   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

Indole Synthesis via Allenyl Ester; Enantioselective Total Synthesis of Geissoschizoline

open access: yesChemistryEurope
Methyl indole‐2‐acetate is a key structural motif in plant‐derived indole alkaloids. In this study, a mild and efficient protocol is presented for its preparation using readily available aniline derivatives, which are synthesized from malonic esters. The
Sohsuke Moriue   +5 more
doaj   +1 more source

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