FDNet: Frequency Domain Denoising Network For Cell Segmentation in Astrocytes Derived From Induced Pluripotent Stem Cells [PDF]
Artificially generated induced pluripotent stem cells (iPSCs) from somatic cells play an important role for disease modeling and drug screening of neurodegenerative diseases. Astrocytes differentiated from iPSCs are important targets to investigate neuronal metabolism.
arxiv
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease [PDF]
Krishanu Saha, Rudolf Jaenisch
openalex +1 more source
Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang+4 more
wiley +1 more source
Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis+7 more
wiley +1 more source
Challenges of Stem Cell Therapy for Spinal Cord Injury: Human Embryonic Stem Cells, Endogenous Neural Stem Cells, or Induced Pluripotent Stem Cells? [PDF]
Mohammad Ronaghi+3 more
openalex +1 more source
Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu+6 more
wiley +1 more source
Hematopoietic and endothelial differentiation of human induced pluripotent stem cells [PDF]
Kyung-Dal Choi+7 more
openalex +1 more source
Induced pluripotent stem cells in disease modelling and drug discovery
R. G. Rowe, G. Daley
semanticscholar +1 more source
Suspended Tissue Open Microfluidic Patterning (STOMP)
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack+22 more
wiley +1 more source
Establishment of mouse induced pluripotent stem cells selected for Nanog expression
Keisuke Okita+2 more
openalex +2 more sources