Results 201 to 210 of about 496,668 (364)

Enhanced generation of hematopoietic cells from human hepatocarcinoma cell−stimulated human embryonic and induced pluripotent stem cells [PDF]

, 2009
Min Lu, Melanie Kardel, Michael D. O’Connor, Connie J. Eaves   +3 more
openalex   +1 more source

Chirality Regulates Stem Cell Fate and Promotes Corneal Epithelial Regeneration via Manipulating Notch Pathway

Advanced Science, EarlyView.
Chirality governs the limbal epithelial stem cell fate. Right‐handed chirality enhances cell proliferation and differentiation, while left‐handed chirality partially maintains cell stemness. By activating the Notch pathway, 3D right‐handed chiral hydrogel offers a drug‐free and cell‐free strategy for effective corneal regeneration.
Shiding Li, Yu Zhao, Junzhao Chen, Beibei Wu, Nianxuan Wu, Hao Sun, Liangbo Chen, Chuanliang Feng, Yao Fu   +8 more
wiley   +1 more source

Stem cell therapy for spinal cord injury: The use of oligodendrocytes and motor neurons derived from human embryonic stem cells

Translational Research in Anatomy, 2015
Over the past few years, the understanding of stem cells as a potential therapeutic source has significantly evolved, and the previous concept of irreparable neural injury is being reconsidered.
Nimer Adeeb, Aman Deep, Nicole Hose, Mona Rezaei, Salman Abbasi Fard, R. Shane Tubbs, Parham Yashar, Mark A. Liker, Babak Kateb, Martin M. Mortazavi   +9 more
doaj  

Tumorigenicity of Human Induced Pluripotent Stem Cells Depends on the Balance of Gene Expression Between P21 and P53 [PDF]

, 2009
Hisashi Moriguchi, Raymond T. Chung, Chifumi Sato   +2 more
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Induced pluripotent stem cells free of exogenous reprogramming factors [PDF]

, 2009
Ramzey Abujarour, Sheng Ding
openalex   +1 more source

PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species

Advanced Science, EarlyView.
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen, Xiaoman Zhu, Michael Mingze Lu, Qingjian Ou, Xueying Wang, Zhenzhen Zhao, Qi Shen, Qian Wang, Zhe Wang, Jing‐Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Xiaoliang Jin, Yanlong Bi, Lixia Lu, Guo‐Tong Xu, Haibin Tian   +19 more
wiley   +1 more source

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

Advanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo, Youngjun Kim, Rian Kang, Seho Lee, Dang Du Nguyen, Soomin Park, Dongjoon Lee, Jong Won Han, Inhee Mook‐Jung, Luke P. Lee, Jong‐Chan Park, Inki Kim   +11 more
wiley   +1 more source

Application of induced pluripotent stem cells in the conservation of endangered animals. [PDF]

Stem Cell Res Ther
Lou J, Li W, Chen P, Chen H, Shakoor A, Chen Y, Hua J, Wang Y, Zhang S.   +8 more
europepmc   +1 more source

Reprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine? [PDF]

, 2009
Roberto Enseñat‐Waser, António Pellicer, Carlos Simón   +2 more
openalex   +1 more source