Results 201 to 210 of about 309,089 (339)

Generation of Human-Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 [PDF]

, 2009
Wenlin Li, Hongyan Zhou, Ramzey Abujarour, Saiyong Zhu, Jin Young Joo, Tongxiang Lin, Ergeng Hao, Hans R. Schöler, Alberto Hayek, Sheng Ding   +9 more
openalex   +1 more source

Induced pluripotent stem cells from a spinal muscular atrophy patient

Nature, 2009
A. Ebert, Junying Yu, F. F. Rose, Virginia B. Mattis, C. Lorson, J. Thomson, C. Svendsen   +6 more
semanticscholar   +1 more source

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

MIXL1 activation in endoderm differentiation of human induced pluripotent stem cells. [PDF]

Stem Cell Reports
Osteil P, Withey S, Santucci N, Aryamanesh N, Pang I, Salehin N, Sun J, Qin A, Su J, Knowles H, Li XB, Cai S, Wolvetang E, Tam PPL.   +13 more
europepmc   +1 more source

Modelling schizophrenia using human induced pluripotent stem cells

Nature, 2011
K. Brennand, A. Simone, J. Jou, Chelsea Gelboin-Burkhart, Ngoc N Tran, Sarah Sangar, Yan Li, Yangling Mu, Gong Chen, Diana Yu, S. McCarthy, J. Sebat, F. Gage   +12 more
semanticscholar   +1 more source

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord. [PDF]

PLoS One
Yamazaki A, Shiozawa S, Koushige Y, Kondo H, Shibuya H, Edamura K.   +5 more
europepmc   +1 more source

An identification of the novel combination therapy for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells [PDF]

, 2009
Hisashi Moriguchi, Raymond T. Chung, Chifumi Sato   +2 more
openalex   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

Infection of human induced pluripotent stem cells by an oncogenic herpesvirus. [PDF]

Front Cell Infect Microbiol
Fan J, Lin Z, Zhang H, Dai L, Qin Z.
europepmc   +1 more source