Results 11 to 20 of about 14,164 (239)
Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives [PDF]
Cell Reports MedicineSummary: Both aging and systemic inflammation are major risk factors for cardiovascular disease. This review summarizes the interrelationship of aging and inflammation—known as inflammaging—and the consequences for cardiovascular health.
Luke Spray +11 more
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, 2019 Inflammaging refers to the chronic, low-grade inflammation that develops with age and may favor the onset of age-related diseases (ARDs) and geriatric syndromes (GSs).
Franceschi C. +5 more
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Melatonin and brain inflammaging [PDF]
Progress in Neurobiology, 2015 : Melatonin is known to possess several properties of value for healthy aging, as a direct and indirect antioxidant, protectant and modulator of mitochondrial function, antiexcitotoxic agent, enhancer of circadian amplitudes, immune modulator and ...
Hardeland, Ruediger +10 more
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Unveiling a novel in-vitro model of skin inflammaging [PDF]
Frontiers in MedicineIntroductionSensitive skin is characterized by a disrupted skin barrier, making it prone to reacting to external stimuli, including UV exposure, air pollution, and cosmetic allergens. Sensitive skin tends to react with oxidative stress factors that could
Ying Xu +7 more
doaj +2 more sources
lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases
Mediators of Inflammation, 2019 Aging and age-related diseases (ARDs) share basic mechanisms largely involving inflammation. A chronic, low-grade, subclinical inflammation called inflammaging occurs during aging.
Lulingxiao Nie +4 more
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Pathogenesis and inflammaging in myelodysplastic syndrome
HaematologicaMyelodysplastic syndromes (MDS) are a genetically complex and phenotypically diverse set of clonal hematologic neoplasms that occur with increasing frequency with age.
Matthew T. Villaume, Michael R. Savona
doaj +3 more sources
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target [PDF]
Frontiers in Immunology, 2019 Inflammation aims to restore tissue homeostasis after injury or infection. Age-related decline of tissue homeostasis causes a physiological low-grade chronic inflammatory phenotype known as inflammaging that is involved in many age-related diseases ...
Freek J. H. Sorgdrager +10 more
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Identification of crucial inflammaging related risk factors in multiple sclerosis [PDF]
Frontiers in Molecular NeuroscienceBackgroundMultiple sclerosis (MS) is an immune-mediated disease characterized by inflammatory demyelinating lesions in the central nervous system. Studies have shown that the inflammation is vital to both the onset and progression of MS, where aging ...
Mengchu Xu +9 more
doaj +2 more sources
As global life expectancy continues to rise we are challenged with maintaining health into old age. One strategy is to target the chronic low level inflammation associated with aging, termed ‘inflammaging’.
Pilkington, Suzanne +3 more
core +11 more sources
Science Translational Medicine, 2020 Metformin reverses an aging-associated inflammatory immune profile. Age is a major risk factor for many life-threatening diseases including cardiometabolic disease, cancer, and neurodegeneration.
Van den Bossche, J
core +2 more sources