Results 11 to 20 of about 15,244 (279)
Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives [PDF]
Cell Reports MedicineSummary: Both aging and systemic inflammation are major risk factors for cardiovascular disease. This review summarizes the interrelationship of aging and inflammation—known as inflammaging—and the consequences for cardiovascular health.
Luke Spray +11 more
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Unveiling a novel in-vitro model of skin inflammaging [PDF]
Frontiers in MedicineIntroductionSensitive skin is characterized by a disrupted skin barrier, making it prone to reacting to external stimuli, including UV exposure, air pollution, and cosmetic allergens. Sensitive skin tends to react with oxidative stress factors that could
Ying Xu +7 more
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Inflammaging, immunosenescence, and cardiovascular aging: insights into long COVID implications [PDF]
Frontiers in Cardiovascular MedicineAging leads to physiological changes, including inflammaging—a chronic low-grade inflammatory state with significant implications for various physiological systems, particularly for cardiovascular health.
Ludmila Müller, Svetlana Di Benedetto
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Inflammaging as a prodrome to Alzheimer's disease [PDF]
Journal of Neuroinflammation, 2008 Recently, the term "inflammaging" was coined by Franceshci and colleagues to characterize a widely accepted paradigm that ageing is accompanied by a low-grade chronic up-regulation of certain pro-inflammatory responses. Inflammaging differs significantly
Rrapo Elona +6 more
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Melatonin and brain inflammaging [PDF]
Progress in Neurobiology, 2015 : Melatonin is known to possess several properties of value for healthy aging, as a direct and indirect antioxidant, protectant and modulator of mitochondrial function, antiexcitotoxic agent, enhancer of circadian amplitudes, immune modulator and ...
Hardeland, Ruediger +10 more
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, 2019 Inflammaging refers to the chronic, low-grade inflammation that develops with age and may favor the onset of age-related diseases (ARDs) and geriatric syndromes (GSs).
Franceschi C. +5 more
core +2 more sources
Cochlear Inflammaging in Relation to Ion Channels and Mitochondrial Functions
Cells, 2021 The slow accumulation of inflammatory biomarker levels in the body—also known as inflammaging—has been linked to a myriad of age-related diseases. Some of these include neurodegenerative conditions such as Parkinson’s disease, obesity, type II diabetes ...
Parveen Bazard +10 more
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Toward precision interventions and metrics of inflammaging
Nature AgingInflammaging describes a chronic, systemic, low-grade inflammatory state that is recognized as a major risk factor for age-related diseases (ARDs) and a pivotal convergence point of multiple biological mechanisms involved in aging.
Franceschi, Claudio +4 more
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lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases
Mediators of Inflammation, 2019 Aging and age-related diseases (ARDs) share basic mechanisms largely involving inflammation. A chronic, low-grade, subclinical inflammation called inflammaging occurs during aging.
Lulingxiao Nie +4 more
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Inflammaging: a new immune–metabolic viewpoint for age-related diseases [PDF]
Nature Reviews Endocrinology, 2018 Ageing and age-related diseases share some basic mechanistic pillars that largely converge on inflammation. During ageing, chronic, sterile, low-grade inflammation — called inflammaging — develops, which contributes to the pathogenesis of age-related ...
Santoro A. +4 more
core +2 more sources