Results 31 to 40 of about 15,244 (279)

Advanced glycation end products induce inflammaging in periodontal ligament fibroblasts through RAGE/AKT/mTOR/glycolysis pathway

Acta Odontologica Scandinavica
Background: Inflammaging plays a pivotal role in the pathogenesis of multiple age-related diseases, including periodontitis. Advanced glycation end products (AGEs) are known to induce inflammaging and exacerbate periodontitis. However, the mechanisms by
Lin Xiong, Jiayu Shu, Hongli Gao, Yufeng Qin, Yuehan Zhang, Xuelian Chang, Qiang Dong, Helin Chen   +7 more
doaj   +2 more sources

Inflammation and aging-related disease: A transdisciplinary inflammaging framework. [PDF]

GeroScience
Inflammaging, a state of chronic, progressive low-grade inflammation during aging, is associated with several adverse clinical outcomes, including frailty, disability, and death.
Lee, Jiha, Andonian, Brian, LaHue, Sara, Litke, Rachel, Hippensteel, Joseph, Sheshadri, Anoop, Boyle, Eileen, Colbert, James, Sherman, Andrea, Nair, Devika, Singh, Namrata, Faye, Adam, Sattui, Sebastian, Devinney, Michael, Kochar, Bharati, Zhang, Yinan, Abuabara, Katrina   +16 more
core   +2 more sources

Anthraquinones and Aloe Vera Extracts as Potential Modulators of Inflammaging Mechanisms: A Translational Approach from Autoimmune to Onco-Hematological Diseases

Molecules
Inflammaging is a chronic, low-grade inflammatory state that contributes to age-related diseases, including cardiovascular disorders, osteoporosis, neurodegeneration, and cancer. This process involves immunosenescence, oxidative stress, and immune aging,
Raffaele Cordiano, Santino Caserta, Paola Lucia Minciullo, Alessandro Allegra, Sebastiano Gangemi   +4 more
doaj   +2 more sources

Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow

Journal of Orthopaedic Translation
Background: Bone marrow inflammaging is a low-grade chronic inflammation that induces bone marrow aging. Multiple age-related and inflammatory diseases involve bone marrow inflammaging.
Peng Liao, Sihan Tong, Lin Du, Jiong Mei, Bingqi Wang, Yafei Lu, Meng Yao, Changqing Zhang, Delin Liu, Zhigang Zhong, Fang Ye, Junjie Gao   +11 more
doaj   +2 more sources

Photothermal Microneedle Hydrogel Patch for Refractory Soft Tissue Injuries through Thermosensitized Anti‐Inflammaging Modulation

Small Structures
Soft tissue injuries (STIs) are the most common cause of extremity pain and motion dysfunction. Persistent inflammatory activation of immune cells characterized by senescence‐associated secretory phenotype (SASP) and mitochondrial stress are considered ...
Wanbo Zhu, Quan Liu, Ziheng Zhang, Yingjie Wang, Jiawei Mei, Dongdong Xu, Jun Zhou, Zheng Su, Xianzuo Zhang, Chen Zhu, Jiaxing Wang, Junchen Zhu, Xiaochun Peng, Xianlong Zhang   +13 more
doaj   +2 more sources

Inflammaging: The Next Challenge—Exploring the Role of Gut Microbiota, Environmental Factors, and Sex Differences

Biomedicines
The term ‘inflammaging’ has been coined to describe the chronic state of inflammation derived from ongoing cycles of tissue damage and the subsequent immune responses.
Mario Caldarelli, Pierluigi Rio, Andrea Marrone, Vincenzo Giambra, Antonio Gasbarrini, Giovanni Gambassi, Rossella Cianci   +6 more
doaj   +2 more sources

Inflammaging is minimal among forager-horticulturalists in the Bolivian Amazon

Proceedings. Biological sciences
An increase in chronic systemic inflammation in later life, termed inflammaging, is implicated in health risk. However, it is unclear whether inflammaging develops in all human populations, or if it is the product of environmental mismatch.
Charifson, M., Cummings, D., Eid Rodriguez, D., Kraft, T., Koebele, S., Woolard, K., Hooper, P., Franck, M., Kaplan, H., Cohen, A., Buetow, K., Aronoff, J., Stieglitz, J., Jenkins, C., Suarez, I., Finch, C., Trumble, B., Gurven, M., Garcia, A., Ghafoor, S., Beheim, B. ; https://orcid.org/   +20 more
core   +3 more sources

Global research trends in inflammaging from 2005 to 2024: a bibliometric analysis

Frontiers in Aging
BackgroundInflammaging, defined as chronic low-grade inflammation associated with aging, is considered a key factor in many age-related diseases. Despite growing research, comprehensive assessments of trends and focuses on this field over the past 2 ...
Beier Jiang, Beier Jiang, Yi-ni Dong, Yu Xiong, Chun-xia Jiang, Jun Ping, Qi Wu, Liu-jun Xu, Liu-jun Xu, Run-zhe Shu, Run-zhe Shu, Dan-dan Gao, Sheng-mei Zhu, Wei-dong Ye, Feng Zhang, Feng Zhang   +15 more
doaj   +2 more sources

Inflammaging and the Lung [PDF]

Clinics in Geriatric Medicine, 2017
With the coming of the "silver tsunami," expanding the knowledge about how various intrinsic and extrinsic factors affect the immune system in the elderly is timely and of immediate clinical need. The global population is increasing in age. By the year 2030, more than 20% of the population of the United States will be older than 65 years of age.
Elizabeth J, Kovacs, Devin M, Boe, Lisbeth A, Boule, Brenda J, Curtis   +3 more
openaire   +2 more sources

Inflammaging and Osteoarthritis. [PDF]

, 2023
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age worldwide. While in the past it was considered a mere consequence of cartilage degradation leading to anatomical and functional joint impairment, in recent decades,
Antonio Sica
core   +1 more source