Results 31 to 40 of about 18,204 (247)
Cells, 2022 A senescence-associated secretory phenotype (SASP) and a mild inflammatory response characteristic of senescent cells (inflammaging) form the conditions for the development of cardiovascular diseases: atherosclerosis, coronary heart disease, and ...
Vladimir Khavinson +4 more
doaj +1 more source
Siglec receptors impact mammalian lifespan by modulating oxidative stress. [PDF]
, 2015 Aging is a multifactorial process that includes the lifelong accumulation of molecular damage, leading to age-related frailty, disability and disease, and eventually death. In this study, we report evidence of a significant correlation between the number
Fu, Xiaoming +16 more
core +1 more source
Cellular Mechanisms of Inflammaging and Periodontal Disease
Frontiers in Dental Medicine, 2022 Increased age is associated with an increased prevalence of chronic inflammatory diseases and conditions. The term inflammaging has been used to describe the age-related changes to the immune response that results in a chronic and elevated inflammatory ...
Daniel Clark +2 more
doaj +1 more source
Inflammation and premature aging in advanced chronic kidney disease [PDF]
, 2017 Systemic inflammation in end-stage renal disease (ESRD) is an established risk factor for mortality and a catalyst for other complications which are related to a premature aging phenotype, including muscle wasting, vascular calcification and other forms ...
Casper G. Schalkwijk +9 more
core +1 more source
Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy
Inflammation and Regeneration, 2023 Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction is essential to initiate healing after injury.
Junichi Kushioka +8 more
doaj +1 more source
Systemic inflammation, body composition, and physical performance in old community-dwellers [PDF]
, 2017 Background Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process. The aim of the present study was to provide a preliminary characterisation of the relationship among these age-related ...
Addison +33 more
core +2 more sources
Microsized inflammaging protects stem cells [PDF]
Blood, 2020 In this issue of Blood, Grants et al have identified connections between reduced expression of microRNA-146a (miR-146a), increased inflammation, impaired hematopoietic stem cell (HSC) quiescence, and a poor prognosis for acute myeloid leukemia (AML).
O'Connell, Ryan M, Rao, Dinesh S
openaire +4 more sources
Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging
Immunity & Ageing, 2020 Immune system aging is characterized by the paradox of immunosenescence (insufficiency) and inflammaging (over-reaction), which incorporate two sides of the same coin, resulting in immune disorder.
Rachel Thomas, Weikan Wang, Dong-Ming Su
doaj +1 more source
Amniotic Epithelial Cells: A New Tool to Combat Aging and Age-Related Diseases? [PDF]
, 2016 The number of elderly people is growing at an unprecedented rate and this increase of the aging population is expected to have a direct impact on the incidence of age-related diseases and healthcare-associated costs. Thus, it is imperative that new tools
Barbara Barboni +4 more
core +2 more sources
lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases
Mediators of Inflammation, 2019 Aging and age-related diseases (ARDs) share basic mechanisms largely involving inflammation. A chronic, low-grade, subclinical inflammation called inflammaging occurs during aging.
Lulingxiao Nie +4 more
doaj +1 more source