Results 31 to 40 of about 14,164 (239)

Inflammaging in Dermatology: A New Frontier for Research [PDF]

, 2021
As humans age, our ability to manage certain types of inflammation is reduced. As a result, we experience chronic, low-grade inflammation, which has been termed "inflammaging".
Woolery-Lloyd, Heather, Haque, Abid
core   +1 more source

Neuro-Inflammaging and Psychopathological Distress

Biomedicines, 2022
Inflammaging is a low degree of chronic and systemic tissue inflammation associated with aging, and is intimately linked to pro-inflammatory mediators. These substances are involved in the pathogenesis of chronic inflammatory diseases and related psychopathological symptoms.
Giuseppe Murdaca, Francesca Paladin, Marco Casciaro, Carmelo Mario Vicario, Sebastiano Gangemi, Gabriella Martino   +5 more
openaire   +5 more sources

Contribution of the inflammasome to inflammaging [PDF]

Journal of Inflammation, 2018
Inflammation is a natural part of the aging process. This process is referred to as inflammaging. Inflammaging has been associated with deleterious outcomes in the aging brain in diseases such as Alzheimer's disease and Parkinson's disease. The inflammasome is a multi-protein complex of the innate immune response involved in the activation of caspase-1
Nancy H. Mejias, Camila C. Martinez, Marisa E. Stephens, Juan Pablo de Rivero Vaccari   +3 more
openaire   +3 more sources

A Mechanism-Based Framework for Anti-Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell-Based Interventions. [PDF]

Aging Cell
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Li F, Wang Y, Wang G, Chen J, Huang S.
europepmc   +2 more sources

Systems medicine of inflammaging [PDF]

Briefings in Bioinformatics, 2015
Systems Medicine (SM) can be defined as an extension of Systems Biology (SB) to Clinical-Epidemiological disciplines through a shifting paradigm, starting from a cellular, toward a patient centered framework. According to this vision, the three pillars of SM are Biomedical hypotheses, experimental data, mainly achieved by Omics technologies and ...
Gastone C. Castellani, Giulia Menichetti, Paolo Garagnani, Maria Giulia Bacalini, Chiara Pirazzini, Claudio Franceschi, Sebastiano Collino, Claudia Sala, Daniel Remondini, Enrico Giampieri, Ettore Mosca, Matteo Bersanelli, Silvia Vitali, Ìtalo Faria do Valle, Pietro Liò, Luciano Milanesi   +15 more
openaire   +6 more sources

The natural history of periodontal disease—Part 2: In populations with access to dental care: The Studies of Health in Pomerania (SHIP)

Periodontology 2000, EarlyView., 2023
Abstract In this descriptive analysis of the 21‐year follow‐up data from the SHIP‐START cohort and the 7‐year follow‐up data from the SHIP‐TREND cohort, we report the progression of clinical attachment levels (CAL), age effects on CAL change, and a detailed description of CAL progression and remission. At baseline, 4307 and 4420 persons participated in
Thomas Kocher, Peter Meisel, Reiner Biffar, Henry Völzke, Birte Holtfreter   +4 more
wiley   +1 more source

Stratum corneum hydration inversely correlates with certain serum cytokine levels in the elderly, possibly contributing to inflammaging

Immunity & Ageing, 2023
Background Chronic, low-grade inflammation, also termed ‘inflammaging’, has been linked to the development of some aging-associated disorders. Recent studies suggest that inflammaging is attributable to aging-associated epidermal dysfunction.
Bin Yang, Chengzhi Lv, Li Ye, Zhen Wang, Yoon Kim, Wenhai Luo, Peter M. Elias, Mao-Qiang Man   +7 more
doaj   +1 more source

Senescence-Associated Secretory Phenotype of Cardiovascular System Cells and Inflammaging: Perspectives of Peptide Regulation

Cells, 2022
A senescence-associated secretory phenotype (SASP) and a mild inflammatory response characteristic of senescent cells (inflammaging) form the conditions for the development of cardiovascular diseases: atherosclerosis, coronary heart disease, and ...
Vladimir Khavinson, Natalia Linkova, Anastasiia Dyatlova, Raisa Kantemirova, Kirill Kozlov   +4 more
doaj   +1 more source

Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging

Immunity & Ageing, 2020
Immune system aging is characterized by the paradox of immunosenescence (insufficiency) and inflammaging (over-reaction), which incorporate two sides of the same coin, resulting in immune disorder.
Rachel Thomas, Weikan Wang, Dong-Ming Su
doaj   +1 more source

Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy

Inflammation and Regeneration, 2023
Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction is essential to initiate healing after injury.
Junichi Kushioka, Simon Kwoon-Ho Chow, Masakazu Toya, Masanori Tsubosaka, Huaishuang Shen, Qi Gao, Xueping Li, Ning Zhang, Stuart B. Goodman   +8 more
doaj   +1 more source