Results 41 to 50 of about 18,204 (247)
Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways [PDF]
, 2017 Original studyXunta de Galicia; ED431B 2016/013Xunta de Galicia; GPC2014/082Xunta de Galicia; IN607C 2016 ...
Fuchs, Dietmar +10 more
core +2 more sources
Unveiling a novel in-vitro model of skin inflammaging
Frontiers in MedicineIntroductionSensitive skin is characterized by a disrupted skin barrier, making it prone to reacting to external stimuli, including UV exposure, air pollution, and cosmetic allergens. Sensitive skin tends to react with oxidative stress factors that could
Ying Xu +7 more
doaj +1 more source
Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of Microglia Activation
Molecules, 2022 Inflammaging is a term used to describe the tight relationship between low-grade chronic inflammation and aging that occurs during physiological aging in the absence of evident infection.
Antonia Cianciulli +3 more
doaj +1 more source
Experimental and Molecular MedicineCellular senescence, recognized as a key hallmark of aging, leads to the accumulation of senescent cells in various tissues over time. While the detrimental effects of these cells on age-related pathological conditions are well-documented, there is still
Soon Sang Park +11 more
doaj +1 more source
Ficolin-2 inhibitors are present in sera after prolonged storage at −80 °C [PDF]
PeerJ, 2016 Ficolins can activate the lectin pathway of the complement system that provides innate immune protection against pathogens, marks host cellular debris for clearance, and promotes inflammation.
Kimball Aaron Geno +4 more
doaj +2 more sources
New Synthetic Endocannabinoid as Anti-Inflammaging Cosmetic Active: an In Vitro Study on a Reconstructed Skin Model [PDF]
, 2019 Endocannabinoids have been recently appointed as interesting cosmetic actives in regulating inflammaging, a state of chronic low-grade inflammation, known for being involved in many senescence\u2019s manifestations, included skin aging.
Caviola, E +3 more
core
Age-related biomarkers can be modulated by diet in the rat
, 2011 This study seeks to establish the normal serum concentrations of biochemical markers related to nutrition, inflammation and disease, and to investigate how the levels change with age and diet in the rat.
Evans, Karen +4 more
core +1 more source
Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]
, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
T cell control of inflammaging
Seminars in Immunology, 2023 T cells are a critical component of the immune system, found in abundance in blood, secondary lymphoid organs, and peripheral tissues. As individuals age, T cells are particularly susceptible to changes, making them one of the most affected immune subsets.
Shchukina, Irina +2 more
openaire +3 more sources