Results 41 to 50 of about 17,832 (233)

Microsized inflammaging protects stem cells [PDF]

Blood, 2020
In this issue of Blood, Grants et al have identified connections between reduced expression of microRNA-146a (miR-146a), increased inflammation, impaired hematopoietic stem cell (HSC) quiescence, and a poor prognosis for acute myeloid leukemia (AML).
O'Connell, Ryan M, Rao, Dinesh S
openaire   +4 more sources

Physical exercise as a preventive procedures inflammation of aging [PDF]

, 2011
Ao longo do processo de envelhecimento observa-se complexa remodelagem do sistema imunitário. Estas alterações estão associadas ao desenvolvimento de patologias responsáveis por grande parte da mortalidade em população idosa.
Barros, Jonatas de França, Brito, Ciro José, Córdova, Claudio Olavo de Almeida, Mendes, Edmar Lacerda, Nóbrega, Otávio de Tolêdo, Roas, Aendria Fernanda Castro Martins, Silva Júnior, Fernando Lopes e, Volp, Ana Carolina Pinheiro   +7 more
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A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]

, 2020
The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan, Campisi, Judith, Ferrucci, Luigi, Holtz, Anja, Jeon, Ok Hee, Kale, Abhijit, Kuehnemann, Chisaka, Payne, Therese, Rao, Chirag, Schilling, Birgit, Shah, Samah, Sharma, Vagisha   +11 more
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One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects:Results From the United Kingdom Arm of the NU-AGE Trial [PDF]

, 2018
Amongst the major features of aging are chronic low grade inflammation and a decline in immune function. The Mediterranean diet (MedDiet) is considered to be a valuable tool to improve health status, and although beneficial effects have been reported, to
Bashir, Berendsen, Casas, Casas, Castle, Cevenini, Cevenini, Clements, De Martinis, Della Bella, Dewan, Esposito, Fragopoulou, Franceschi, Franceschi, Franceschi, Franceschi, Gayoso, Jani, Jing, Lee, Lencel, Li, Li, Maijó, Man, Martinez-Gonzalez, Mena, Monti, Pae, Pedersen, Peralbo, Peregrin, Prietl, Pérez-Cabezas, Quezada, Rea, Robinson, Santangelo, Santoro, Shelnutt, Shodell, Stout-Delgado, Tortorella, Varadhan, Vasto, Yamamoto   +46 more
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Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of Microglia Activation

Molecules, 2022
Inflammaging is a term used to describe the tight relationship between low-grade chronic inflammation and aging that occurs during physiological aging in the absence of evident infection.
Antonia Cianciulli, Rosa Calvello, Melania Ruggiero, Maria Antonietta Panaro   +3 more
doaj   +1 more source

Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age [PDF]

, 2015
Background: Chronic low-grade inflammation is considered a driver of many age-related disorders, including vascular diseases (inflammaging). Inhibition of autophagic capacity with ageing was postulated to generate a pro-inflammatory condition via ...
Böckler, Dittmar, Dihlmann, Susanne, Hakimi, Maani, Wortmann, Markus, Wu, Xiaoyu, Zhang, Jian   +5 more
core   +1 more source

Unveiling a novel in-vitro model of skin inflammaging

Frontiers in Medicine
IntroductionSensitive skin is characterized by a disrupted skin barrier, making it prone to reacting to external stimuli, including UV exposure, air pollution, and cosmetic allergens. Sensitive skin tends to react with oxidative stress factors that could
Ying Xu, Yue Liu, Junxiang Li, Yao Li, Linlin Xu, Kun Dong, Xiao Lin, Tao Zhang   +7 more
doaj   +1 more source

Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation [PDF]

, 2018
The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments.
Chatzinikolaou, Athanasios, Chondrogianni, Niki, Deli, Chariklia K, Draganidis, Dimitrios, Fatouros, Ioannis G, Georgakouli, Kalliopi, Jamurtas, Athanasios Z, Karagounis, Leonidas G, Koutedakis, Yiannis, Laschou, Vasiliki C, Michalopoulou, Maria, Papadopoulos, Constantinos, Papanikolaou, Konstantinos, Stampoulis, Theodoros, Tsimeas, Panagiotis   +14 more
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Rcor2 underexpression in senescent mice: a target for inflammaging? [PDF]

, 2014
[Background] Aging is characterized by a low-grade systemic inflammation that contributes to the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD).
María J Alvarez-López, Patricia Molina-Martínez, Marco Castro-Freire, Marta Cosín-Tomás, Rosa Cristòfol, Marcelina Párrizas, Rosa Escorihuela, Merce Pallàs, Coral Sanfeliu, Perla Kaliman   +9 more
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Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target

Frontiers in Immunology, 2019
Inflammation aims to restore tissue homeostasis after injury or infection. Age-related decline of tissue homeostasis causes a physiological low-grade chronic inflammatory phenotype known as inflammaging that is involved in many age-related diseases ...
Freek J. H. Sorgdrager, Freek J. H. Sorgdrager, Freek J. H. Sorgdrager, Freek J. H. Sorgdrager, Petrus J. W. Naudé, Petrus J. W. Naudé, Ido P. Kema, Ellen A. Nollen, Peter P. De Deyn, Peter P. De Deyn, Peter P. De Deyn   +10 more
doaj   +1 more source