Results 231 to 240 of about 35,568 (289)

Mitochondria and polycystic ovary syndrome: The role of ferroptosis, inflammasomes, and endoplasmic reticulum stress. [PDF]

Int J Biol Sci
Zhang X, Sun T, Wang X, Ma Y, Cao L, Tan J.   +5 more
europepmc   +1 more source

Neuroinflammation in Alzheimer's Disease (AD) and Glioblastoma (GBM): Shared Mechanisms and Therapeutic Insights. [PDF]

Cells
Mikołajczak K, Chmiel J, Leszek J.
europepmc   +1 more source

Inflammasome activation dictates the efficacy of antimycobacterial activity of frontline TB drugs. [PDF]

PLoS Pathog
Singh A, Bisht K, Maurya G, Yadav N, Nanda R, Rao V.   +5 more
europepmc   +1 more source

The Multifaceted Role of Pyroptosis: Molecular Mechanisms, Crosstalk with Other Cell Death Pathways, and Therapeutic Implications. [PDF]

MedComm (2020)
Boaru DL, De Castro-Martinez P, Garcia-Montero C, Fraile-Martinez O, Alhaddadin MNM, Barrena-Blázquez S, Lopez-Gonzalez L, Fernández CT, Alvarado-Hurtado R, Giménez TR, Lasa-Unzúe I, Alonso MD, Gutiérrez-Calvo A, Saez MA, Cobo-Prieto D, Saz JV, Alvarez-Mon M, Diaz-Pedrero R, Ortega MA.   +18 more
europepmc   +1 more source

The NLRP3-α-Synuclein Circuit: A Core Driver and Therapeutic Target in Parkinson's Disease. [PDF]

J Inflamm Res
Liu K, He Z, Zhang L, Wu YM, Xiao L.
europepmc   +1 more source

Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophages. [PDF]

PLoS Pathog
Kulkarni M, Bourne CM, Mahale AB, Exconde PM, Murphy C, Goodrow HT, Cervantes S, Kardhashi M, Kambayashi M, Yoo W, Wrong TJ, Patio RC, Discher BM, Taabazuing CY.   +13 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

MircoRNAs as regulators of regulated cell death in cancer progression: a focus on ferroptosis, anoikis and pyroptosis. [PDF]

Front Pharmacol
Xiao D, Luo Y, Liu L, Lu Y, Xie X, Zhou Z, Ma B, Peng F.   +7 more
europepmc   +1 more source

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött, Glenn Geidel, Carmen M. T. Roeper, Lucija Ačkar, Bente Siebels, Hannah Voß, Hartmut Schlüter, Michaela Schweizer, Kilian Müller, Alessandra Rünger, Tim Zell, Benjamin Deitert, Ali Zeinal‐Abedini, Isabel Heidrich, Stefan W. Schneider, Klaus Pantel, Daniel J. Smit, Christoffer Gebhardt   +17 more
wiley   +1 more source