Results 101 to 110 of about 1,145,138 (308)

Exploring the Causal Relationship Between Inflammatory Bowel Disease and Bell's Palsy Based on Inflammatory Proteins: A Mendelian Randomization Study

Brain and Behavior
Background The relationship between inflammatory bowel disease (IBD) and Bell's palsy remains unsubstantiated. This study aims to investigate the causal relationship between IBD and Bell's palsy.
Daofeng Fan, Wenbao Wu, Jiaqian Dai, Yinjuan Chen, Qingqing Lian, Changbo Zhao, Binfu Que, Rui Qiu   +7 more
doaj   +1 more source

Genetic information supports a causal relationship between trace elements, inflammatory proteins, and COPD: evidence from a Mendelian randomization analysis

Frontiers in Nutrition
ObjectiveDietary factors and nutritional status may be among the risk factors for Chronic Obstructive Pulmonary Disease (COPD). There exists a certain correlation between trace elements and COPD.
Zhenghua Cao, Shengkun Zhao, Tong Wu, Feng Sun, Huan Ding, Shaodan Hu, Li Shi   +6 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]

, 2010
Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick, Zitta, Karina, Grünewald, Matthias Lars, Albrecht, Martin, Zacharowski, Kai, Lucius, Ralph, Hensler, Johannes, Bein, Berthold, Fösel, Nikola   +8 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effect of diet type on serum and faecal concentration of S100/calgranulins in the captive cheetah [PDF]

, 2014
Gastrointestinal disease is omnipresent in captive cheetahs (Acinonyx jubatus), in contrast to its freeranging populations. The current study aimed to evaluate the effect of diet type (meat-only whole prey) on gastrointestinal health in captive cheetahs ...
Depauw, S, Heilmann, RM, Hesta, M, Whitehouse-Tedd, K, Steiner, JM, Janssens, GPJ, Suchodolski, JS   +6 more
core  

The Effect of Thymoquinone on Liver Function and Inflammatory Gene Expression in an Animal Model of Metabolic Dysfunction-Associated Fatty Liver Disease [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: Metabolic dysfunction-associated fatty liver disease (MAFLD) is now widely recognized as the hepatic presentation of the metabolic syndrome.
F Koohpeyma, MR Koohpeyma, M Kaviani, N Montazeri-Najafabady, S Dastghaib, M Shams   +5 more
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Beyond glucose: wearable and implantable biosensors for continuous monitoring of metabolic, hormonal, and inflammatory biomarkers in personalized cardiometabolic care

Frontiers in Bioengineering and Biotechnology
Wearable and implantable biosensors are shifting biochemical assessment from episodic laboratory testing to continuous, context-rich physiological monitoring.
Hong Cai, Yehui He, Chaoyue Wang, Yiqun Zhao, Chunhui Yang   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source